Chitosan supported ionic liquid (CSIL): An excellent catalyst for one-pot synthesis of bis(indolyl)methanes

In this present communication, one-pot synthesis of bis(indolyl)methane derivatives (3a-t) achieved from the condensation of indole (1) with various substituted benzaldehydes (2a-t) using [DSIM][AlCl3]x-@CS chitosan supported ionic liquid (CSIL) as catalyst in ethanol at mild reaction was reported....

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Main Authors: Gajrali M. Patel, Abhijeet S. Kure, Gajanan G. Mandawad, Baliram S. Hote, Shankaraiah G. Konda
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715622001552
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author Gajrali M. Patel
Abhijeet S. Kure
Gajanan G. Mandawad
Baliram S. Hote
Shankaraiah G. Konda
author_facet Gajrali M. Patel
Abhijeet S. Kure
Gajanan G. Mandawad
Baliram S. Hote
Shankaraiah G. Konda
author_sort Gajrali M. Patel
collection DOAJ
description In this present communication, one-pot synthesis of bis(indolyl)methane derivatives (3a-t) achieved from the condensation of indole (1) with various substituted benzaldehydes (2a-t) using [DSIM][AlCl3]x-@CS chitosan supported ionic liquid (CSIL) as catalyst in ethanol at mild reaction was reported. The main advantage of this present methodology using chitosan supported ionic liquid was leads to effective formation of products were achieved under optimized condition without an inert atmosphere. In addition to this, shorter reaction time, simple work-up procedure, easy preparation of the catalyst and chemoselectivity were significantly noted. Further, the newly synthesized compounds were fully characterized by the spectroscopic methods.
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spelling doaj.art-b8c00aba3716404196891aa963cd551b2022-12-22T03:53:12ZengElsevierResults in Chemistry2211-71562022-01-014100436Chitosan supported ionic liquid (CSIL): An excellent catalyst for one-pot synthesis of bis(indolyl)methanesGajrali M. Patel0Abhijeet S. Kure1Gajanan G. Mandawad2Baliram S. Hote3Shankaraiah G. Konda4Government Polytechnic College, Shivajinagar, Pune 411016, Maharashtra, IndiaDepartment of Chemistry, MIT College, Loha 431606, Maharashtra, IndiaDepartment of Chemistry, Maharashtra Udayagiri Mahavidyalaya, Udgir 413517, Maharashtra, IndiaDepartment of Chemistry, Maharashtra Udayagiri Mahavidyalaya, Udgir 413517, Maharashtra, IndiaDepartment of Chemistry, K. J. Somaiya College, Kopargaon-423601, Ahmednagar, Maharashtra, India; Corresponding author.In this present communication, one-pot synthesis of bis(indolyl)methane derivatives (3a-t) achieved from the condensation of indole (1) with various substituted benzaldehydes (2a-t) using [DSIM][AlCl3]x-@CS chitosan supported ionic liquid (CSIL) as catalyst in ethanol at mild reaction was reported. The main advantage of this present methodology using chitosan supported ionic liquid was leads to effective formation of products were achieved under optimized condition without an inert atmosphere. In addition to this, shorter reaction time, simple work-up procedure, easy preparation of the catalyst and chemoselectivity were significantly noted. Further, the newly synthesized compounds were fully characterized by the spectroscopic methods.http://www.sciencedirect.com/science/article/pii/S2211715622001552IndoleBis(indolyl)methaneChitosan supported ionic liquid (CSIL)Efficient synthesis
spellingShingle Gajrali M. Patel
Abhijeet S. Kure
Gajanan G. Mandawad
Baliram S. Hote
Shankaraiah G. Konda
Chitosan supported ionic liquid (CSIL): An excellent catalyst for one-pot synthesis of bis(indolyl)methanes
Results in Chemistry
Indole
Bis(indolyl)methane
Chitosan supported ionic liquid (CSIL)
Efficient synthesis
title Chitosan supported ionic liquid (CSIL): An excellent catalyst for one-pot synthesis of bis(indolyl)methanes
title_full Chitosan supported ionic liquid (CSIL): An excellent catalyst for one-pot synthesis of bis(indolyl)methanes
title_fullStr Chitosan supported ionic liquid (CSIL): An excellent catalyst for one-pot synthesis of bis(indolyl)methanes
title_full_unstemmed Chitosan supported ionic liquid (CSIL): An excellent catalyst for one-pot synthesis of bis(indolyl)methanes
title_short Chitosan supported ionic liquid (CSIL): An excellent catalyst for one-pot synthesis of bis(indolyl)methanes
title_sort chitosan supported ionic liquid csil an excellent catalyst for one pot synthesis of bis indolyl methanes
topic Indole
Bis(indolyl)methane
Chitosan supported ionic liquid (CSIL)
Efficient synthesis
url http://www.sciencedirect.com/science/article/pii/S2211715622001552
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