HAEMATOLOGICAL AND CYTOPATHOLOGICAL ALTERATIONS IN THEILERIA ANNULATA INDUCED BOVINE LYMPHADENOPATHY
The tick-borne intra-cellular parasite, Theileria annulata, causes mortality in bovines. Schizont of the parasite in lymphocytes divides continuously stimulating the clonal expansion of lymphoid cells in lymph nodes leading to the neoplasticlike lymphoid cell proliferation and sometimes may also ca...
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| Format: | Article |
| Language: | English |
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West Bengal Veterinary Alumni Association
2022-12-01
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| Series: | Exploratory Animal and Medical Research |
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| Online Access: | https://www.animalmedicalresearch.org/Vol.12_Issue-2_December_2022/HAEMATOLOGICAL%20%20AND%20CYTOPATHOLO.pdf |
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| author | Mohanapriya Thangaraj S.B. Gavade Geeta Devi Leishangthem Ashwani Kumar Sharma |
| author_facet | Mohanapriya Thangaraj S.B. Gavade Geeta Devi Leishangthem Ashwani Kumar Sharma |
| author_sort | Mohanapriya Thangaraj |
| collection | DOAJ |
| description | The tick-borne intra-cellular parasite, Theileria annulata, causes mortality in bovines. Schizont of the parasite
in lymphocytes divides continuously stimulating the clonal expansion of lymphoid cells in lymph nodes leading to the neoplasticlike lymphoid cell proliferation and sometimes may also cause lymphoma, especially in chronic conditions. Two cattle, with a
history of fever and respiratory distress, were presented to the Large Animal Unit, Teaching Veterinary Clinical Complex,
GADVASU. On clinical examination, the animals had a high fever (106-107ºF), anemia, icteric mucus membranes, and prescapular
lymph node enlargement. Whole blood and fine needle aspirate from the lymph node were collected. A blood smear examination
revealed anemia, leucopenia with relative lymphocytosis, and thrombocytopenia. Further, there was the presence of schizonts
(Koch blue bodies) in the lymphocytes and piroplasms of T. annulata in the red blood cells. Lymph node aspirate examination
revealed the feature that mimics lymphoma by the presence of a monomorphic population of lymphoblasts and with all stages of
mitotic figures along with lymphoglandular bodies. Numerous schizonts were also recorded in the lymphoblasts during the
examination of lymph node aspirate. |
| first_indexed | 2024-04-10T20:23:28Z |
| format | Article |
| id | doaj.art-b8c5e18bb0a4474594a3d1eedea7ac8b |
| institution | Directory Open Access Journal |
| issn | 2277-470X 2319-247X |
| language | English |
| last_indexed | 2024-04-10T20:23:28Z |
| publishDate | 2022-12-01 |
| publisher | West Bengal Veterinary Alumni Association |
| record_format | Article |
| series | Exploratory Animal and Medical Research |
| spelling | doaj.art-b8c5e18bb0a4474594a3d1eedea7ac8b2023-01-25T13:55:49ZengWest Bengal Veterinary Alumni AssociationExploratory Animal and Medical Research2277-470X2319-247X2022-12-0112227327610.52635/eamr/12.2.273-276HAEMATOLOGICAL AND CYTOPATHOLOGICAL ALTERATIONS IN THEILERIA ANNULATA INDUCED BOVINE LYMPHADENOPATHYMohanapriya Thangaraj0S.B. Gavade1Geeta Devi Leishangthem 2Ashwani Kumar Sharma3Department of Veterinary Pathology, Department of Veterinary Medicine, COVS, Guru Angad Dev Veterinary and Animal Science University, Ludhiana, Punjab- 141004, India.Department of Veterinary Pathology, Department of Veterinary Medicine, COVS, Guru Angad Dev Veterinary and Animal Science University, Ludhiana, Punjab- 141004, India.Department of Veterinary Pathology, Department of Veterinary Medicine, COVS, Guru Angad Dev Veterinary and Animal Science University, Ludhiana, Punjab- 141004, India.Department of Veterinary Pathology, Department of Veterinary Medicine, COVS, Guru Angad Dev Veterinary and Animal Science University, Ludhiana, Punjab- 141004, India.The tick-borne intra-cellular parasite, Theileria annulata, causes mortality in bovines. Schizont of the parasite in lymphocytes divides continuously stimulating the clonal expansion of lymphoid cells in lymph nodes leading to the neoplasticlike lymphoid cell proliferation and sometimes may also cause lymphoma, especially in chronic conditions. Two cattle, with a history of fever and respiratory distress, were presented to the Large Animal Unit, Teaching Veterinary Clinical Complex, GADVASU. On clinical examination, the animals had a high fever (106-107ºF), anemia, icteric mucus membranes, and prescapular lymph node enlargement. Whole blood and fine needle aspirate from the lymph node were collected. A blood smear examination revealed anemia, leucopenia with relative lymphocytosis, and thrombocytopenia. Further, there was the presence of schizonts (Koch blue bodies) in the lymphocytes and piroplasms of T. annulata in the red blood cells. Lymph node aspirate examination revealed the feature that mimics lymphoma by the presence of a monomorphic population of lymphoblasts and with all stages of mitotic figures along with lymphoglandular bodies. Numerous schizonts were also recorded in the lymphoblasts during the examination of lymph node aspirate. https://www.animalmedicalresearch.org/Vol.12_Issue-2_December_2022/HAEMATOLOGICAL%20%20AND%20CYTOPATHOLO.pdfbovinekoch blue bodieslymphadenopathytheileria annulata |
| spellingShingle | Mohanapriya Thangaraj S.B. Gavade Geeta Devi Leishangthem Ashwani Kumar Sharma HAEMATOLOGICAL AND CYTOPATHOLOGICAL ALTERATIONS IN THEILERIA ANNULATA INDUCED BOVINE LYMPHADENOPATHY Exploratory Animal and Medical Research bovine koch blue bodies lymphadenopathy theileria annulata |
| title | HAEMATOLOGICAL AND CYTOPATHOLOGICAL ALTERATIONS IN THEILERIA ANNULATA INDUCED BOVINE LYMPHADENOPATHY |
| title_full | HAEMATOLOGICAL AND CYTOPATHOLOGICAL ALTERATIONS IN THEILERIA ANNULATA INDUCED BOVINE LYMPHADENOPATHY |
| title_fullStr | HAEMATOLOGICAL AND CYTOPATHOLOGICAL ALTERATIONS IN THEILERIA ANNULATA INDUCED BOVINE LYMPHADENOPATHY |
| title_full_unstemmed | HAEMATOLOGICAL AND CYTOPATHOLOGICAL ALTERATIONS IN THEILERIA ANNULATA INDUCED BOVINE LYMPHADENOPATHY |
| title_short | HAEMATOLOGICAL AND CYTOPATHOLOGICAL ALTERATIONS IN THEILERIA ANNULATA INDUCED BOVINE LYMPHADENOPATHY |
| title_sort | haematological and cytopathological alterations in theileria annulata induced bovine lymphadenopathy |
| topic | bovine koch blue bodies lymphadenopathy theileria annulata |
| url | https://www.animalmedicalresearch.org/Vol.12_Issue-2_December_2022/HAEMATOLOGICAL%20%20AND%20CYTOPATHOLO.pdf |
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