Efficacy of Electroconvulsive Therapy and Ketamine Therapy in Major Depressive Disorder; A Comparative Study
Objective: To evaluate and compare the efficacy of Electroconvulsive therapy (ECT) and Ketamine infusions in hospitalized patients suffering from major depressive disorder (MDD). Study Design: Comparative cross-sectional study. Place and duration of study: Armed Forces Institute of Mental Hea...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Army Medical College Rawalpindi
2023-02-01
|
Series: | Pakistan Armed Forces Medical Journal |
Subjects: | |
Online Access: | https://www.pafmj.org/index.php/PAFMJ/article/view/8818 |
Summary: | Objective: To evaluate and compare the efficacy of Electroconvulsive therapy (ECT) and Ketamine infusions in hospitalized patients suffering from major depressive disorder (MDD).
Study Design: Comparative cross-sectional study.
Place and duration of study: Armed Forces Institute of Mental Health, Rawalpindi Pakistan, from Feb to Apr 2021.
Methodology: Forty in-patients diagnosed as having MDD were randomly allocated ECT/Ketamine intervention as per international standards. Either group of patients acted as a control for the other. Their Beck Depressive Inventory (BDI) scores before and after the completion of treatment cycles were assessed to determine their response to treatment.
Results: The Ketamine-Group showed fewer depressive symptoms than the ECT Group. The depressive symptoms were reduced in 16(80.78%) patients after Ketamine infusions, while 15(77.78%) patients showed improvement after ECT sessions.In addition, the response to Ketamine was quicker.
Conclusion: This study has reported that low dose Ketamine has a more rapid impact than Electroconvulsive therapy in improving symptoms of depression in major depressive disorder patients.
|
---|---|
ISSN: | 0030-9648 2411-8842 |