Efficacy of Electroconvulsive Therapy and Ketamine Therapy in Major Depressive Disorder; A Comparative Study
Objective: To evaluate and compare the efficacy of Electroconvulsive therapy (ECT) and Ketamine infusions in hospitalized patients suffering from major depressive disorder (MDD). Study Design: Comparative cross-sectional study. Place and duration of study: Armed Forces Institute of Mental Hea...
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| Format: | Article |
| Language: | English |
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Army Medical College Rawalpindi
2023-02-01
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| Series: | Pakistan Armed Forces Medical Journal |
| Subjects: | |
| Online Access: | https://www.pafmj.org/index.php/PAFMJ/article/view/8818 |
| _version_ | 1797856301519208448 |
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| author | Asif Azeem Bajwa Sohail Ali Sikandar Ali Khan Nida Saleem Tashfeen Bin Nazir |
| author_facet | Asif Azeem Bajwa Sohail Ali Sikandar Ali Khan Nida Saleem Tashfeen Bin Nazir |
| author_sort | Asif Azeem Bajwa |
| collection | DOAJ |
| description |
Objective: To evaluate and compare the efficacy of Electroconvulsive therapy (ECT) and Ketamine infusions in hospitalized patients suffering from major depressive disorder (MDD).
Study Design: Comparative cross-sectional study.
Place and duration of study: Armed Forces Institute of Mental Health, Rawalpindi Pakistan, from Feb to Apr 2021.
Methodology: Forty in-patients diagnosed as having MDD were randomly allocated ECT/Ketamine intervention as per international standards. Either group of patients acted as a control for the other. Their Beck Depressive Inventory (BDI) scores before and after the completion of treatment cycles were assessed to determine their response to treatment.
Results: The Ketamine-Group showed fewer depressive symptoms than the ECT Group. The depressive symptoms were reduced in 16(80.78%) patients after Ketamine infusions, while 15(77.78%) patients showed improvement after ECT sessions.In addition, the response to Ketamine was quicker.
Conclusion: This study has reported that low dose Ketamine has a more rapid impact than Electroconvulsive therapy in improving symptoms of depression in major depressive disorder patients.
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| first_indexed | 2024-04-09T20:38:15Z |
| format | Article |
| id | doaj.art-b8c6ec7a0810416a818357494c4012f4 |
| institution | Directory Open Access Journal |
| issn | 0030-9648 2411-8842 |
| language | English |
| last_indexed | 2024-04-09T20:38:15Z |
| publishDate | 2023-02-01 |
| publisher | Army Medical College Rawalpindi |
| record_format | Article |
| series | Pakistan Armed Forces Medical Journal |
| spelling | doaj.art-b8c6ec7a0810416a818357494c4012f42023-03-30T06:25:31ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422023-02-0173110.51253/pafmj.v73i1.8818Efficacy of Electroconvulsive Therapy and Ketamine Therapy in Major Depressive Disorder; A Comparative StudyAsif Azeem Bajwa0Sohail Ali1Sikandar Ali Khan2Nida Saleem3Tashfeen Bin Nazir4Armed Forces Institute of Mental Health/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Mental Health/National University of Medical Sciences (NUMS) Rawalpindi PakistanCombined Military Hospital, Mangla/ National University of Medical Sciences (NUMS) PakistanArmed Forces Institute of Mental Health/National University of Medical Sciences (NUMS) Rawalpindi PakistanNational University of Medical Sciences (NUMS) Rawalpindi Pakistan Objective: To evaluate and compare the efficacy of Electroconvulsive therapy (ECT) and Ketamine infusions in hospitalized patients suffering from major depressive disorder (MDD). Study Design: Comparative cross-sectional study. Place and duration of study: Armed Forces Institute of Mental Health, Rawalpindi Pakistan, from Feb to Apr 2021. Methodology: Forty in-patients diagnosed as having MDD were randomly allocated ECT/Ketamine intervention as per international standards. Either group of patients acted as a control for the other. Their Beck Depressive Inventory (BDI) scores before and after the completion of treatment cycles were assessed to determine their response to treatment. Results: The Ketamine-Group showed fewer depressive symptoms than the ECT Group. The depressive symptoms were reduced in 16(80.78%) patients after Ketamine infusions, while 15(77.78%) patients showed improvement after ECT sessions.In addition, the response to Ketamine was quicker. Conclusion: This study has reported that low dose Ketamine has a more rapid impact than Electroconvulsive therapy in improving symptoms of depression in major depressive disorder patients. https://www.pafmj.org/index.php/PAFMJ/article/view/8818Electroconvulsive therapyECT versus ketamineKetamineMajor depressive disorder |
| spellingShingle | Asif Azeem Bajwa Sohail Ali Sikandar Ali Khan Nida Saleem Tashfeen Bin Nazir Efficacy of Electroconvulsive Therapy and Ketamine Therapy in Major Depressive Disorder; A Comparative Study Pakistan Armed Forces Medical Journal Electroconvulsive therapy ECT versus ketamine Ketamine Major depressive disorder |
| title | Efficacy of Electroconvulsive Therapy and Ketamine Therapy in Major Depressive Disorder; A Comparative Study |
| title_full | Efficacy of Electroconvulsive Therapy and Ketamine Therapy in Major Depressive Disorder; A Comparative Study |
| title_fullStr | Efficacy of Electroconvulsive Therapy and Ketamine Therapy in Major Depressive Disorder; A Comparative Study |
| title_full_unstemmed | Efficacy of Electroconvulsive Therapy and Ketamine Therapy in Major Depressive Disorder; A Comparative Study |
| title_short | Efficacy of Electroconvulsive Therapy and Ketamine Therapy in Major Depressive Disorder; A Comparative Study |
| title_sort | efficacy of electroconvulsive therapy and ketamine therapy in major depressive disorder a comparative study |
| topic | Electroconvulsive therapy ECT versus ketamine Ketamine Major depressive disorder |
| url | https://www.pafmj.org/index.php/PAFMJ/article/view/8818 |
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