Protein with negative surface charge distribution, Bnr1, shows characteristics of a DNA‐mimic protein and may be involved in the adaptation of Burkholderia cenocepacia

Protein with negative surface charge distribution, Bnr1, shows characteristics of a DNA‐mimic protein and may be involved in the adaptation of Burkholderia cenocepacia

Abstract Adaptation of opportunistic pathogens to their host environment requires reprogramming of a vast array of genes to facilitate survival in the host. Burkholderia cenocepacia, a Gram‐negative bacterium with a large genome of ∼8 Mb that colonizes environmental niches, is exquisitely adaptable...

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Bibliographic Details
Main Authors: Ruth Dennehy, Niamh Duggan, Simon Dignam, Sarah McCormack, Eugene Dillon, Jessica Molony, Maria Romano, Yueran Hou, Laura Ardill, Matthew V. X. Whelan, Zuzanna Drulis‐Kawa, Tadhg Ó'Cróinín, Miguel A. Valvano, Rita Berisio, Siobhán McClean
Format: Article
Language:English
Published: Wiley 2022-02-01
Series:MicrobiologyOpen
Subjects:
bacterial adaptation
Burkholderia cenocepacia
chronic infection
cystic fibrosis
DNA‐mimic protein
protein–protein interaction
Online Access:https://doi.org/10.1002/mbo3.1264

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