Serrated adenocarcinoma of sigmoid colon with mismatch repair protein‐proficient phenotype: Histopathological recognition of a new subtype of colorectal adenocarcinoma
Key Clinical Message Serrated adenocarcinoma is a distinct subtype of colorectal carcinoma characterized by unique histological and molecular features. Here we present a case study of a 58‐year‐old female patient who presented with generalized weakness, abdominal discomfort, and per‐rectal bleeding....
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-03-01
|
| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.8669 |
| _version_ | 1797244367710191616 |
|---|---|
| author | Diksha Karki Sajan Ngakhusi |
| author_facet | Diksha Karki Sajan Ngakhusi |
| author_sort | Diksha Karki |
| collection | DOAJ |
| description | Key Clinical Message Serrated adenocarcinoma is a distinct subtype of colorectal carcinoma characterized by unique histological and molecular features. Here we present a case study of a 58‐year‐old female patient who presented with generalized weakness, abdominal discomfort, and per‐rectal bleeding. This case report highlights the importance of understanding the histopathological features of serrated adenocarcinoma for accurate diagnosis which has impact on further management. |
| first_indexed | 2024-04-24T19:09:53Z |
| format | Article |
| id | doaj.art-b8ccfa7905a24d4bb3d95dacacb1ee60 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-04-24T19:09:53Z |
| publishDate | 2024-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-b8ccfa7905a24d4bb3d95dacacb1ee602024-03-26T12:36:43ZengWileyClinical Case Reports2050-09042024-03-01123n/an/a10.1002/ccr3.8669Serrated adenocarcinoma of sigmoid colon with mismatch repair protein‐proficient phenotype: Histopathological recognition of a new subtype of colorectal adenocarcinomaDiksha Karki0Sajan Ngakhusi1Department of Pathology Bhaktapur Cancer Hospital Bhaktapur Bagmati NepalDepartment of Pathology Bhaktapur Cancer Hospital Bhaktapur Bagmati NepalKey Clinical Message Serrated adenocarcinoma is a distinct subtype of colorectal carcinoma characterized by unique histological and molecular features. Here we present a case study of a 58‐year‐old female patient who presented with generalized weakness, abdominal discomfort, and per‐rectal bleeding. This case report highlights the importance of understanding the histopathological features of serrated adenocarcinoma for accurate diagnosis which has impact on further management.https://doi.org/10.1002/ccr3.8669adenocarcinomacolonoscopycolorectal carcinomahistopathologysigmoid colon |
| spellingShingle | Diksha Karki Sajan Ngakhusi Serrated adenocarcinoma of sigmoid colon with mismatch repair protein‐proficient phenotype: Histopathological recognition of a new subtype of colorectal adenocarcinoma Clinical Case Reports adenocarcinoma colonoscopy colorectal carcinoma histopathology sigmoid colon |
| title | Serrated adenocarcinoma of sigmoid colon with mismatch repair protein‐proficient phenotype: Histopathological recognition of a new subtype of colorectal adenocarcinoma |
| title_full | Serrated adenocarcinoma of sigmoid colon with mismatch repair protein‐proficient phenotype: Histopathological recognition of a new subtype of colorectal adenocarcinoma |
| title_fullStr | Serrated adenocarcinoma of sigmoid colon with mismatch repair protein‐proficient phenotype: Histopathological recognition of a new subtype of colorectal adenocarcinoma |
| title_full_unstemmed | Serrated adenocarcinoma of sigmoid colon with mismatch repair protein‐proficient phenotype: Histopathological recognition of a new subtype of colorectal adenocarcinoma |
| title_short | Serrated adenocarcinoma of sigmoid colon with mismatch repair protein‐proficient phenotype: Histopathological recognition of a new subtype of colorectal adenocarcinoma |
| title_sort | serrated adenocarcinoma of sigmoid colon with mismatch repair protein proficient phenotype histopathological recognition of a new subtype of colorectal adenocarcinoma |
| topic | adenocarcinoma colonoscopy colorectal carcinoma histopathology sigmoid colon |
| url | https://doi.org/10.1002/ccr3.8669 |
| work_keys_str_mv | AT dikshakarki serratedadenocarcinomaofsigmoidcolonwithmismatchrepairproteinproficientphenotypehistopathologicalrecognitionofanewsubtypeofcolorectaladenocarcinoma AT sajanngakhusi serratedadenocarcinomaofsigmoidcolonwithmismatchrepairproteinproficientphenotypehistopathologicalrecognitionofanewsubtypeofcolorectaladenocarcinoma |