PD-1+ IFN-γ+ subset of CD8+ T cell in circulation predicts response to anti–PD-1 therapy in NSCLC

PD-1+ IFN-γ+ subset of CD8+ T cell in circulation predicts response to anti–PD-1 therapy in NSCLC

BackgroundTreatment with programmed cell death protein-1 (PD-1) antibodies has minimal response rates in patients with non–small cell lung cancer (NSCLC), and, actually, they are treated with chemotherapy combined with anti–PD-1 therapy clinically. Reliable markers based on circulating immune cell s...

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Bibliographic Details
Main Authors: Wenxiu Chen, Yiting Hua, Conghui Shan, Jia Wei, Yutong Zhou, Shiyang Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Oncology
Subjects:
PD-1
IFN-γ
NSCLC
circulation
chemotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1182301/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1182301/full

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