Task-based functional neuroimaging in infants: a systematic review
BackgroundInfancy is characterized by rapid neurological transformations leading to consolidation of lifelong function capabilities. Studying the infant brain is crucial for understanding how these mechanisms develop during this sensitive period. We review the neuroimaging modalities used with infan...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-08-01
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| Series: | Frontiers in Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2023.1233990/full |
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| author | Kofi Agyeman Tristan McCarty Harpreet Multani Kamryn Mattingly Katherine Koziar Jason Chu Jason Chu Charles Liu Charles Liu Elena Kokkoni Vassilios Christopoulos Vassilios Christopoulos Vassilios Christopoulos |
| author_facet | Kofi Agyeman Tristan McCarty Harpreet Multani Kamryn Mattingly Katherine Koziar Jason Chu Jason Chu Charles Liu Charles Liu Elena Kokkoni Vassilios Christopoulos Vassilios Christopoulos Vassilios Christopoulos |
| author_sort | Kofi Agyeman |
| collection | DOAJ |
| description | BackgroundInfancy is characterized by rapid neurological transformations leading to consolidation of lifelong function capabilities. Studying the infant brain is crucial for understanding how these mechanisms develop during this sensitive period. We review the neuroimaging modalities used with infants in stimulus-induced activity paradigms specifically, for the unique opportunity the latter provide for assessment of brain function.MethodsConducted a systematic review of literature published between 1977–2021, via a comprehensive search of four major databases. Standardized appraisal tools and inclusion/exclusion criteria were set according to the PRISMA guidelines.ResultsTwo-hundred and thirteen papers met the criteria of the review process. The results show clear evidence of overall cumulative growth in the number of infant functional neuroimaging studies, with electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) to be the most utilized and fastest growing modalities with behaving infants. However, there is a high level of exclusion rates associated with technical limitations, leading to limited motor control studies (about 6%) in this population.ConclusionAlthough the use of functional neuroimaging modalities with infants increases, there are impediments to effective adoption of existing technologies with this population. Developing new imaging modalities and experimental designs to monitor brain activity in awake and behaving infants is vital. |
| first_indexed | 2024-03-12T14:33:38Z |
| format | Article |
| id | doaj.art-b8cefdd58ee94175a509b6d2058c8bb5 |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-03-12T14:33:38Z |
| publishDate | 2023-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-b8cefdd58ee94175a509b6d2058c8bb52023-08-17T12:19:20ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2023-08-011710.3389/fnins.2023.12339901233990Task-based functional neuroimaging in infants: a systematic reviewKofi Agyeman0Tristan McCarty1Harpreet Multani2Kamryn Mattingly3Katherine Koziar4Jason Chu5Jason Chu6Charles Liu7Charles Liu8Elena Kokkoni9Vassilios Christopoulos10Vassilios Christopoulos11Vassilios Christopoulos12Department of Bioengineering, University of California, Riverside, Riverside, CA, United StatesDepartment of Bioengineering, University of California, Riverside, Riverside, CA, United StatesDepartment of Bioengineering, University of California, Riverside, Riverside, CA, United StatesNeuroscience Graduate Program, University of California, Riverside, Riverside, CA, United StatesOrbach Science Library, University of California, Riverside, Riverside, CA, United StatesDivision of Neurosurgery, Children’s Hospital Los Angeles, Los Angeles, CA, United StatesDepartment of Neurological Surgery, University of Southern California, Los Angeles, CA, United StatesUSC Neurorestoration Center, University of Southern California, Los Angeles, CA, United StatesDepartment of Neurological Surgery, University of Southern California, Los Angeles, CA, United StatesDepartment of Bioengineering, University of California, Riverside, Riverside, CA, United StatesDepartment of Bioengineering, University of California, Riverside, Riverside, CA, United StatesNeuroscience Graduate Program, University of California, Riverside, Riverside, CA, United StatesDepartment of Neurological Surgery, University of Southern California, Los Angeles, CA, United StatesBackgroundInfancy is characterized by rapid neurological transformations leading to consolidation of lifelong function capabilities. Studying the infant brain is crucial for understanding how these mechanisms develop during this sensitive period. We review the neuroimaging modalities used with infants in stimulus-induced activity paradigms specifically, for the unique opportunity the latter provide for assessment of brain function.MethodsConducted a systematic review of literature published between 1977–2021, via a comprehensive search of four major databases. Standardized appraisal tools and inclusion/exclusion criteria were set according to the PRISMA guidelines.ResultsTwo-hundred and thirteen papers met the criteria of the review process. The results show clear evidence of overall cumulative growth in the number of infant functional neuroimaging studies, with electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) to be the most utilized and fastest growing modalities with behaving infants. However, there is a high level of exclusion rates associated with technical limitations, leading to limited motor control studies (about 6%) in this population.ConclusionAlthough the use of functional neuroimaging modalities with infants increases, there are impediments to effective adoption of existing technologies with this population. Developing new imaging modalities and experimental designs to monitor brain activity in awake and behaving infants is vital.https://www.frontiersin.org/articles/10.3389/fnins.2023.1233990/fulltask-based neuroimagingfunctional neuroimaginginfants (0 to 24 months)brain developmentmotor developmentmotor system |
| spellingShingle | Kofi Agyeman Tristan McCarty Harpreet Multani Kamryn Mattingly Katherine Koziar Jason Chu Jason Chu Charles Liu Charles Liu Elena Kokkoni Vassilios Christopoulos Vassilios Christopoulos Vassilios Christopoulos Task-based functional neuroimaging in infants: a systematic review Frontiers in Neuroscience task-based neuroimaging functional neuroimaging infants (0 to 24 months) brain development motor development motor system |
| title | Task-based functional neuroimaging in infants: a systematic review |
| title_full | Task-based functional neuroimaging in infants: a systematic review |
| title_fullStr | Task-based functional neuroimaging in infants: a systematic review |
| title_full_unstemmed | Task-based functional neuroimaging in infants: a systematic review |
| title_short | Task-based functional neuroimaging in infants: a systematic review |
| title_sort | task based functional neuroimaging in infants a systematic review |
| topic | task-based neuroimaging functional neuroimaging infants (0 to 24 months) brain development motor development motor system |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2023.1233990/full |
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