Temperature impacts SARS-CoV-2 spike fusogenicity and evolution

Temperature impacts SARS-CoV-2 spike fusogenicity and evolution

ABSTRACTSARS-CoV-2 infects both the upper and lower respiratory tracts, which are characterized by different temperatures (33°C and 37°C, respectively). In addition, fever is a common COVID-19 symptom. SARS-CoV-2 has been shown to replicate more efficiently at low temperatures, but the effect of tem...

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Bibliographic Details
Main Authors: Jérémy Dufloo, Rafael Sanjuán
Format: Article
Language:English
Published: American Society for Microbiology 2024-04-01
Series:mBio
Subjects:
SARS-CoV-2 spike
temperature
experimental evolution
cell-to-cell fusion
SARS-CoV-2 variants
Online Access:https://journals.asm.org/doi/10.1128/mbio.03360-23

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