Fabrication of Gold Nanostructures on Quartz Crystal Microbalance Surface Using Nanoimprint Lithography for Sensing Applications

A quartz crystal microbalance (QCM) is a sensor that uses the piezoelectric properties of quartz crystals sandwiched between conductive electrodes. Localized surface plasmon resonance (LSPR) is an analytical technique that uses the collective vibration of free electrons on metal surfaces. These meas...

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Main Authors: Ryosuke Nishitsuji, Kenji Sueyoshi, Hideaki Hisamoto, Tatsuro Endo
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/13/9/1430
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author Ryosuke Nishitsuji
Kenji Sueyoshi
Hideaki Hisamoto
Tatsuro Endo
author_facet Ryosuke Nishitsuji
Kenji Sueyoshi
Hideaki Hisamoto
Tatsuro Endo
author_sort Ryosuke Nishitsuji
collection DOAJ
description A quartz crystal microbalance (QCM) is a sensor that uses the piezoelectric properties of quartz crystals sandwiched between conductive electrodes. Localized surface plasmon resonance (LSPR) is an analytical technique that uses the collective vibration of free electrons on metal surfaces. These measurements are known as analysis techniques that use metal surfaces and have been applied as biosensors because they allow for the label-free monitoring of biomolecular binding reactions. These measurements can be used in combination to analyze the reactions that occur on metal surfaces because different types of information can be obtained from them. However, as different devices are used for these measurements, the results often contain device-to-device errors and are not accurately evaluated. In this study, we directly fabricated gold nanostructures on the surface of a QCM to create a device that can simultaneously measure the mass and refractive index information of the analyte. In addition, the device could be easily fabricated because nanoimprint lithography was used to fabricate gold nanostructures. As a proof of concept, the nanoparticle adsorption on gold nanostructures was evaluated, and it was observed that mass and refractive index information were successfully obtained without device-to-device errors.
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spelling doaj.art-b8d2e48a18334018ae3b66d2e79f20182023-11-23T17:49:24ZengMDPI AGMicromachines2072-666X2022-08-01139143010.3390/mi13091430Fabrication of Gold Nanostructures on Quartz Crystal Microbalance Surface Using Nanoimprint Lithography for Sensing ApplicationsRyosuke Nishitsuji0Kenji Sueyoshi1Hideaki Hisamoto2Tatsuro Endo3Department of Applied Chemistry, Graduate School of Engineering, Osaka Metropolitan University, 1-1 Gakuencho, Nakaku, Sakai 599-8531, Osaka, JapanDepartment of Applied Chemistry, Graduate School of Engineering, Osaka Metropolitan University, 1-1 Gakuencho, Nakaku, Sakai 599-8531, Osaka, JapanDepartment of Applied Chemistry, Graduate School of Engineering, Osaka Metropolitan University, 1-1 Gakuencho, Nakaku, Sakai 599-8531, Osaka, JapanDepartment of Applied Chemistry, Graduate School of Engineering, Osaka Metropolitan University, 1-1 Gakuencho, Nakaku, Sakai 599-8531, Osaka, JapanA quartz crystal microbalance (QCM) is a sensor that uses the piezoelectric properties of quartz crystals sandwiched between conductive electrodes. Localized surface plasmon resonance (LSPR) is an analytical technique that uses the collective vibration of free electrons on metal surfaces. These measurements are known as analysis techniques that use metal surfaces and have been applied as biosensors because they allow for the label-free monitoring of biomolecular binding reactions. These measurements can be used in combination to analyze the reactions that occur on metal surfaces because different types of information can be obtained from them. However, as different devices are used for these measurements, the results often contain device-to-device errors and are not accurately evaluated. In this study, we directly fabricated gold nanostructures on the surface of a QCM to create a device that can simultaneously measure the mass and refractive index information of the analyte. In addition, the device could be easily fabricated because nanoimprint lithography was used to fabricate gold nanostructures. As a proof of concept, the nanoparticle adsorption on gold nanostructures was evaluated, and it was observed that mass and refractive index information were successfully obtained without device-to-device errors.https://www.mdpi.com/2072-666X/13/9/1430quartz crystal microbalancelocalized surface plasmon resonancenanoimprint lithographysensor
spellingShingle Ryosuke Nishitsuji
Kenji Sueyoshi
Hideaki Hisamoto
Tatsuro Endo
Fabrication of Gold Nanostructures on Quartz Crystal Microbalance Surface Using Nanoimprint Lithography for Sensing Applications
Micromachines
quartz crystal microbalance
localized surface plasmon resonance
nanoimprint lithography
sensor
title Fabrication of Gold Nanostructures on Quartz Crystal Microbalance Surface Using Nanoimprint Lithography for Sensing Applications
title_full Fabrication of Gold Nanostructures on Quartz Crystal Microbalance Surface Using Nanoimprint Lithography for Sensing Applications
title_fullStr Fabrication of Gold Nanostructures on Quartz Crystal Microbalance Surface Using Nanoimprint Lithography for Sensing Applications
title_full_unstemmed Fabrication of Gold Nanostructures on Quartz Crystal Microbalance Surface Using Nanoimprint Lithography for Sensing Applications
title_short Fabrication of Gold Nanostructures on Quartz Crystal Microbalance Surface Using Nanoimprint Lithography for Sensing Applications
title_sort fabrication of gold nanostructures on quartz crystal microbalance surface using nanoimprint lithography for sensing applications
topic quartz crystal microbalance
localized surface plasmon resonance
nanoimprint lithography
sensor
url https://www.mdpi.com/2072-666X/13/9/1430
work_keys_str_mv AT ryosukenishitsuji fabricationofgoldnanostructuresonquartzcrystalmicrobalancesurfaceusingnanoimprintlithographyforsensingapplications
AT kenjisueyoshi fabricationofgoldnanostructuresonquartzcrystalmicrobalancesurfaceusingnanoimprintlithographyforsensingapplications
AT hideakihisamoto fabricationofgoldnanostructuresonquartzcrystalmicrobalancesurfaceusingnanoimprintlithographyforsensingapplications
AT tatsuroendo fabricationofgoldnanostructuresonquartzcrystalmicrobalancesurfaceusingnanoimprintlithographyforsensingapplications