MpsAB is important for Staphylococcus aureus virulence and growth at atmospheric CO2 levels
The mechanisms behind CO2 dependency in non-autotrophic bacterial isolates are unclear. Here the authors show that the Staphylococcus aureus mpsAB operon is crucial for growth at atmospheric CO2 levels, and provide evidence indicating that MpsAB represents a bicarbonate concentrating system.
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2019-08-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-11547-5 |
| _version_ | 1819036149577940992 |
|---|---|
| author | Sook-Ha Fan Patrick Ebner Sebastian Reichert Tobias Hertlein Susanne Zabel Aditya Kumar Lankapalli Kay Nieselt Knut Ohlsen Friedrich Götz |
| author_facet | Sook-Ha Fan Patrick Ebner Sebastian Reichert Tobias Hertlein Susanne Zabel Aditya Kumar Lankapalli Kay Nieselt Knut Ohlsen Friedrich Götz |
| author_sort | Sook-Ha Fan |
| collection | DOAJ |
| description | The mechanisms behind CO2 dependency in non-autotrophic bacterial isolates are unclear. Here the authors show that the Staphylococcus aureus mpsAB operon is crucial for growth at atmospheric CO2 levels, and provide evidence indicating that MpsAB represents a bicarbonate concentrating system. |
| first_indexed | 2024-12-21T08:00:56Z |
| format | Article |
| id | doaj.art-b8d30b9c5f924af08aec9fe10876005d |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-21T08:00:56Z |
| publishDate | 2019-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-b8d30b9c5f924af08aec9fe10876005d2022-12-21T19:10:54ZengNature PortfolioNature Communications2041-17232019-08-0110111210.1038/s41467-019-11547-5MpsAB is important for Staphylococcus aureus virulence and growth at atmospheric CO2 levelsSook-Ha Fan0Patrick Ebner1Sebastian Reichert2Tobias Hertlein3Susanne Zabel4Aditya Kumar Lankapalli5Kay Nieselt6Knut Ohlsen7Friedrich Götz8Microbial Genetics, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), University of TübingenMicrobial Genetics, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), University of TübingenMicrobial Genetics, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), University of TübingenInstitute for Molecular Infection Biology (IMIB), University of WürzburgCenter for Bioinformatics Tübingen, University of Tübingen, Sand 14Department of Archaeogenetics, Max Planck Institute for the Science of Human HistoryCenter for Bioinformatics Tübingen, University of Tübingen, Sand 14Institute for Molecular Infection Biology (IMIB), University of WürzburgMicrobial Genetics, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), University of TübingenThe mechanisms behind CO2 dependency in non-autotrophic bacterial isolates are unclear. Here the authors show that the Staphylococcus aureus mpsAB operon is crucial for growth at atmospheric CO2 levels, and provide evidence indicating that MpsAB represents a bicarbonate concentrating system.https://doi.org/10.1038/s41467-019-11547-5 |
| spellingShingle | Sook-Ha Fan Patrick Ebner Sebastian Reichert Tobias Hertlein Susanne Zabel Aditya Kumar Lankapalli Kay Nieselt Knut Ohlsen Friedrich Götz MpsAB is important for Staphylococcus aureus virulence and growth at atmospheric CO2 levels Nature Communications |
| title | MpsAB is important for Staphylococcus aureus virulence and growth at atmospheric CO2 levels |
| title_full | MpsAB is important for Staphylococcus aureus virulence and growth at atmospheric CO2 levels |
| title_fullStr | MpsAB is important for Staphylococcus aureus virulence and growth at atmospheric CO2 levels |
| title_full_unstemmed | MpsAB is important for Staphylococcus aureus virulence and growth at atmospheric CO2 levels |
| title_short | MpsAB is important for Staphylococcus aureus virulence and growth at atmospheric CO2 levels |
| title_sort | mpsab is important for staphylococcus aureus virulence and growth at atmospheric co2 levels |
| url | https://doi.org/10.1038/s41467-019-11547-5 |
| work_keys_str_mv | AT sookhafan mpsabisimportantforstaphylococcusaureusvirulenceandgrowthatatmosphericco2levels AT patrickebner mpsabisimportantforstaphylococcusaureusvirulenceandgrowthatatmosphericco2levels AT sebastianreichert mpsabisimportantforstaphylococcusaureusvirulenceandgrowthatatmosphericco2levels AT tobiashertlein mpsabisimportantforstaphylococcusaureusvirulenceandgrowthatatmosphericco2levels AT susannezabel mpsabisimportantforstaphylococcusaureusvirulenceandgrowthatatmosphericco2levels AT adityakumarlankapalli mpsabisimportantforstaphylococcusaureusvirulenceandgrowthatatmosphericco2levels AT kaynieselt mpsabisimportantforstaphylococcusaureusvirulenceandgrowthatatmosphericco2levels AT knutohlsen mpsabisimportantforstaphylococcusaureusvirulenceandgrowthatatmosphericco2levels AT friedrichgotz mpsabisimportantforstaphylococcusaureusvirulenceandgrowthatatmosphericco2levels |