Key Inflammatory Processes in Human NASH Are Reflected in Ldlr−/−.Leiden Mice: A Translational Gene Profiling Study
Introduction: It is generally accepted that metabolic inflammation in the liver is an important driver of disease progression in NASH and associated matrix remodeling/fibrosis. However, the exact molecular inflammatory mechanisms are poorly defined in human studies. Investigation of key pathogenic m...
Main Authors: | Martine C. Morrison, Robert Kleemann, Arianne van Koppen, Roeland Hanemaaijer, Lars Verschuren |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-02-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fphys.2018.00132/full |
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