Dual regulation of Arabidopsis AGO2 by arginine methylation
AGO2 is a core component of the RNAi machinery and contributes to plant immunity during bacterial infection. Here the authors show that AGO2 activity is suppressed by arginine methylation which not only promotes AGO2 degradation but also recruits TSN proteins to degrade AGO2-associated small RNAs.
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2019-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-08787-w |
| _version_ | 1818682356626620416 |
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| author | Po Hu Hongwei Zhao Pei Zhu Yongsheng Xiao Weili Miao Yinsheng Wang Hailing Jin |
| author_facet | Po Hu Hongwei Zhao Pei Zhu Yongsheng Xiao Weili Miao Yinsheng Wang Hailing Jin |
| author_sort | Po Hu |
| collection | DOAJ |
| description | AGO2 is a core component of the RNAi machinery and contributes to plant immunity during bacterial infection. Here the authors show that AGO2 activity is suppressed by arginine methylation which not only promotes AGO2 degradation but also recruits TSN proteins to degrade AGO2-associated small RNAs. |
| first_indexed | 2024-12-17T10:17:33Z |
| format | Article |
| id | doaj.art-b8d3c80b350e4fce9685f67c9f82325f |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-17T10:17:33Z |
| publishDate | 2019-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-b8d3c80b350e4fce9685f67c9f82325f2022-12-21T21:52:52ZengNature PortfolioNature Communications2041-17232019-02-0110111010.1038/s41467-019-08787-wDual regulation of Arabidopsis AGO2 by arginine methylationPo Hu0Hongwei Zhao1Pei Zhu2Yongsheng Xiao3Weili Miao4Yinsheng Wang5Hailing Jin6Department of Microbiology & Plant Pathology, Center for Plant Cell Biology, Institute for Integrative Genome Biology, University of CaliforniaDepartment of Microbiology & Plant Pathology, Center for Plant Cell Biology, Institute for Integrative Genome Biology, University of CaliforniaDepartment of Microbiology & Plant Pathology, Center for Plant Cell Biology, Institute for Integrative Genome Biology, University of CaliforniaDepartment of Chemistry, Center for Plant Cell Biology, Institute for Integrative Genome Biology, University of CaliforniaDepartment of Chemistry, Center for Plant Cell Biology, Institute for Integrative Genome Biology, University of CaliforniaDepartment of Chemistry, Center for Plant Cell Biology, Institute for Integrative Genome Biology, University of CaliforniaDepartment of Microbiology & Plant Pathology, Center for Plant Cell Biology, Institute for Integrative Genome Biology, University of CaliforniaAGO2 is a core component of the RNAi machinery and contributes to plant immunity during bacterial infection. Here the authors show that AGO2 activity is suppressed by arginine methylation which not only promotes AGO2 degradation but also recruits TSN proteins to degrade AGO2-associated small RNAs.https://doi.org/10.1038/s41467-019-08787-w |
| spellingShingle | Po Hu Hongwei Zhao Pei Zhu Yongsheng Xiao Weili Miao Yinsheng Wang Hailing Jin Dual regulation of Arabidopsis AGO2 by arginine methylation Nature Communications |
| title | Dual regulation of Arabidopsis AGO2 by arginine methylation |
| title_full | Dual regulation of Arabidopsis AGO2 by arginine methylation |
| title_fullStr | Dual regulation of Arabidopsis AGO2 by arginine methylation |
| title_full_unstemmed | Dual regulation of Arabidopsis AGO2 by arginine methylation |
| title_short | Dual regulation of Arabidopsis AGO2 by arginine methylation |
| title_sort | dual regulation of arabidopsis ago2 by arginine methylation |
| url | https://doi.org/10.1038/s41467-019-08787-w |
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