Evaluation of ventricular repolarization variables in pediatric COVID-19
INTRODUCTION: Although the childhood clinic of COVID-19 is more innocent than adults, its unknown aspects continue to cause concern among pediatricians. One of these unsettling aspects is the cardiovascular system effects. We investigate the role of ventricular repolarization parameters in predictin...
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| Format: | Article |
| Language: | English |
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Sakarya University
2021-09-01
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| Series: | Sakarya Tıp Dergisi |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/1785424 |
| _version_ | 1827377808342515712 |
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| author | Pınar Dervişoğlu Taliha Öner Bahri Elmas Onur Bircan |
| author_facet | Pınar Dervişoğlu Taliha Öner Bahri Elmas Onur Bircan |
| author_sort | Pınar Dervişoğlu |
| collection | DOAJ |
| description | INTRODUCTION: Although the childhood clinic of COVID-19 is more innocent than adults, its unknown aspects continue to cause concern among pediatricians. One of these unsettling aspects is the cardiovascular system effects. We investigate the role of ventricular repolarization parameters in predicting arrhythmia risk in pediatric COVID-19.
METHODS: Twelve-channel surface electrocardiograms of a total of 166 participants, including children diagnosed with COVID-19 and healthy controls, were analyzed. The QT interval, corrected QT interval, QTc dispersion, Tpeak-Tend, Tp-e dispersion, Tp-e / QT and Tp-e / QTc ratio were calculated. The correlations between ventricular repolarization parameters and laboratory values were examined.
RESULTS: In our study, the COVID-19 patients had a significantly longer Tpeak-Tend (64.51 ± 8.64 and 57.62 ± 7.96; p < 0.001), Tp-e dispersion (21.77 ± 6.4 and 18.01 ± 6.78; p < 0.001), and corrected QT interval (393.18 ± 20.06 and 380 ± 22.3; p < 0.001) duration than the control group. There was a significantly higher Tp-e / QT ratio (0.17 ± 0.02 and 0.15 ± 0.02; p < 0.001), Tp-e / QTc ratio (0.16 ± 0.02 and 0.15 ± 0.02; p < 0.001) in group with COVID-19 than the controls. In addition a positive correlation was found between Tpeak-Tend interval, Tp-e dispersion and white blood cells in the group with SARS CoV2 infection.
DISCUSSION AND CONCLUSION: Evaluating these ventricular repolarization parameters in pediatric SARS CoV2 infection may be useful in predicting the risk of ventricular arrhythmia. |
| first_indexed | 2024-03-08T12:45:39Z |
| format | Article |
| id | doaj.art-b8d7991fcf084aa7ae43a7d046e99487 |
| institution | Directory Open Access Journal |
| issn | 2146-409X |
| language | English |
| last_indexed | 2024-03-08T12:45:39Z |
| publishDate | 2021-09-01 |
| publisher | Sakarya University |
| record_format | Article |
| series | Sakarya Tıp Dergisi |
| spelling | doaj.art-b8d7991fcf084aa7ae43a7d046e994872024-01-21T07:40:08ZengSakarya UniversitySakarya Tıp Dergisi2146-409X2021-09-0111347347810.31832/smj.94205728Evaluation of ventricular repolarization variables in pediatric COVID-19Pınar Dervişoğlu0Taliha Öner1Bahri Elmas2Onur Bircan3SAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜSAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL ÜMRANİYE SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜSAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜSAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜINTRODUCTION: Although the childhood clinic of COVID-19 is more innocent than adults, its unknown aspects continue to cause concern among pediatricians. One of these unsettling aspects is the cardiovascular system effects. We investigate the role of ventricular repolarization parameters in predicting arrhythmia risk in pediatric COVID-19. METHODS: Twelve-channel surface electrocardiograms of a total of 166 participants, including children diagnosed with COVID-19 and healthy controls, were analyzed. The QT interval, corrected QT interval, QTc dispersion, Tpeak-Tend, Tp-e dispersion, Tp-e / QT and Tp-e / QTc ratio were calculated. The correlations between ventricular repolarization parameters and laboratory values were examined. RESULTS: In our study, the COVID-19 patients had a significantly longer Tpeak-Tend (64.51 ± 8.64 and 57.62 ± 7.96; p < 0.001), Tp-e dispersion (21.77 ± 6.4 and 18.01 ± 6.78; p < 0.001), and corrected QT interval (393.18 ± 20.06 and 380 ± 22.3; p < 0.001) duration than the control group. There was a significantly higher Tp-e / QT ratio (0.17 ± 0.02 and 0.15 ± 0.02; p < 0.001), Tp-e / QTc ratio (0.16 ± 0.02 and 0.15 ± 0.02; p < 0.001) in group with COVID-19 than the controls. In addition a positive correlation was found between Tpeak-Tend interval, Tp-e dispersion and white blood cells in the group with SARS CoV2 infection. DISCUSSION AND CONCLUSION: Evaluating these ventricular repolarization parameters in pediatric SARS CoV2 infection may be useful in predicting the risk of ventricular arrhythmia.https://dergipark.org.tr/tr/download/article-file/1785424covid-19childventricular repolarization abnormalitycovid-19çocukventriküler repolarizasyon anormalliği |
| spellingShingle | Pınar Dervişoğlu Taliha Öner Bahri Elmas Onur Bircan Evaluation of ventricular repolarization variables in pediatric COVID-19 Sakarya Tıp Dergisi covid-19 child ventricular repolarization abnormality covid-19 çocuk ventriküler repolarizasyon anormalliği |
| title | Evaluation of ventricular repolarization variables in pediatric COVID-19 |
| title_full | Evaluation of ventricular repolarization variables in pediatric COVID-19 |
| title_fullStr | Evaluation of ventricular repolarization variables in pediatric COVID-19 |
| title_full_unstemmed | Evaluation of ventricular repolarization variables in pediatric COVID-19 |
| title_short | Evaluation of ventricular repolarization variables in pediatric COVID-19 |
| title_sort | evaluation of ventricular repolarization variables in pediatric covid 19 |
| topic | covid-19 child ventricular repolarization abnormality covid-19 çocuk ventriküler repolarizasyon anormalliği |
| url | https://dergipark.org.tr/tr/download/article-file/1785424 |
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