Impact of lung block shape on cardiac dose for total body irradiation
Evaluating cardiac dose during total body irradiation (TBI) is of increasing interest. A three-dimensional beam model for TBI was commissioned and lung shielding was simulated in a treatment planning system with the cardiac silhouette partially blocked and unblocked. When blocked, the median heart d...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-01-01
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| Series: | Physics and Imaging in Radiation Oncology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405631622000045 |
| _version_ | 1818296562749538304 |
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| author | Mallory C. Glenn Kent Wallner Samuel M.H. Luk Ralph Ermoian Yolanda D. Tseng Mark Phillips Minsun Kim |
| author_facet | Mallory C. Glenn Kent Wallner Samuel M.H. Luk Ralph Ermoian Yolanda D. Tseng Mark Phillips Minsun Kim |
| author_sort | Mallory C. Glenn |
| collection | DOAJ |
| description | Evaluating cardiac dose during total body irradiation (TBI) is of increasing interest. A three-dimensional beam model for TBI was commissioned and lung shielding was simulated in a treatment planning system with the cardiac silhouette partially blocked and unblocked. When blocked, the median heart dose decreased by 6% (IQR = 6%) and the median cardiac V12Gy decreased by 27% (IQR = 17%). The median left anterior descending artery dose decreased 20% (IQR = 12%) for blocked cases. Because using partial heart shielding may result in considerable changes in dose to cardiac structures, TBI protocols should explicitly consider lung block design parameters and their potential effects. |
| first_indexed | 2024-12-13T04:05:31Z |
| format | Article |
| id | doaj.art-b8d9a2f0f41c449bb9895b59bdbe54d2 |
| institution | Directory Open Access Journal |
| issn | 2405-6316 |
| language | English |
| last_indexed | 2024-12-13T04:05:31Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Physics and Imaging in Radiation Oncology |
| spelling | doaj.art-b8d9a2f0f41c449bb9895b59bdbe54d22022-12-22T00:00:12ZengElsevierPhysics and Imaging in Radiation Oncology2405-63162022-01-01213034Impact of lung block shape on cardiac dose for total body irradiationMallory C. Glenn0Kent Wallner1Samuel M.H. Luk2Ralph Ermoian3Yolanda D. Tseng4Mark Phillips5Minsun Kim6Department of Radiation Oncology, University of Washington, Seattle, WA, United States; Corresponding author at: Department of Radiation Oncology, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, United States.Department of Radiation Oncology, University of Washington, Seattle, WA, United StatesDepartment of Radiation Oncology, University of Washington, Seattle, WA, United StatesDepartment of Radiation Oncology, University of Washington, Seattle, WA, United StatesDepartment of Radiation Oncology, University of Washington, Seattle, WA, United States; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United StatesDepartment of Radiation Oncology, University of Washington, Seattle, WA, United StatesDepartment of Radiation Oncology, University of Washington, Seattle, WA, United StatesEvaluating cardiac dose during total body irradiation (TBI) is of increasing interest. A three-dimensional beam model for TBI was commissioned and lung shielding was simulated in a treatment planning system with the cardiac silhouette partially blocked and unblocked. When blocked, the median heart dose decreased by 6% (IQR = 6%) and the median cardiac V12Gy decreased by 27% (IQR = 17%). The median left anterior descending artery dose decreased 20% (IQR = 12%) for blocked cases. Because using partial heart shielding may result in considerable changes in dose to cardiac structures, TBI protocols should explicitly consider lung block design parameters and their potential effects.http://www.sciencedirect.com/science/article/pii/S2405631622000045RadiationOncologyTotalBodyHeartBlocks |
| spellingShingle | Mallory C. Glenn Kent Wallner Samuel M.H. Luk Ralph Ermoian Yolanda D. Tseng Mark Phillips Minsun Kim Impact of lung block shape on cardiac dose for total body irradiation Physics and Imaging in Radiation Oncology Radiation Oncology Total Body Heart Blocks |
| title | Impact of lung block shape on cardiac dose for total body irradiation |
| title_full | Impact of lung block shape on cardiac dose for total body irradiation |
| title_fullStr | Impact of lung block shape on cardiac dose for total body irradiation |
| title_full_unstemmed | Impact of lung block shape on cardiac dose for total body irradiation |
| title_short | Impact of lung block shape on cardiac dose for total body irradiation |
| title_sort | impact of lung block shape on cardiac dose for total body irradiation |
| topic | Radiation Oncology Total Body Heart Blocks |
| url | http://www.sciencedirect.com/science/article/pii/S2405631622000045 |
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