Tracheobronchial amyloidosis managed with multimodality therapies

Amyloidosis is a systemic disease involving abnormal extracellular deposition of amyloid and autologous fibrillar protein material in β-pleated sheets. Accumulation of this abnormal protein leads to organ dysfunction, although respiratory tract involvement is rare. We present two cases of tracheobro...

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Main Authors: Philip Sommer, Gagan Kumar, Randolph J. Lipchik, Jayshil J. Patel
Format: Article
Language:English
Published: SAGE Publishing 2014-04-01
Series:Therapeutic Advances in Respiratory Disease
Online Access:https://doi.org/10.1177/1753465814524470
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author Philip Sommer
Gagan Kumar
Randolph J. Lipchik
Jayshil J. Patel
author_facet Philip Sommer
Gagan Kumar
Randolph J. Lipchik
Jayshil J. Patel
author_sort Philip Sommer
collection DOAJ
description Amyloidosis is a systemic disease involving abnormal extracellular deposition of amyloid and autologous fibrillar protein material in β-pleated sheets. Accumulation of this abnormal protein leads to organ dysfunction, although respiratory tract involvement is rare. We present two cases of tracheobronchial amyloidosis successfully treated with surgery and radiation.
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spelling doaj.art-b8d9ed9f788a400e9233df961b94153d2022-12-22T01:55:46ZengSAGE PublishingTherapeutic Advances in Respiratory Disease1753-46581753-46662014-04-01810.1177/1753465814524470Tracheobronchial amyloidosis managed with multimodality therapiesPhilip SommerGagan KumarRandolph J. LipchikJayshil J. PatelAmyloidosis is a systemic disease involving abnormal extracellular deposition of amyloid and autologous fibrillar protein material in β-pleated sheets. Accumulation of this abnormal protein leads to organ dysfunction, although respiratory tract involvement is rare. We present two cases of tracheobronchial amyloidosis successfully treated with surgery and radiation.https://doi.org/10.1177/1753465814524470
spellingShingle Philip Sommer
Gagan Kumar
Randolph J. Lipchik
Jayshil J. Patel
Tracheobronchial amyloidosis managed with multimodality therapies
Therapeutic Advances in Respiratory Disease
title Tracheobronchial amyloidosis managed with multimodality therapies
title_full Tracheobronchial amyloidosis managed with multimodality therapies
title_fullStr Tracheobronchial amyloidosis managed with multimodality therapies
title_full_unstemmed Tracheobronchial amyloidosis managed with multimodality therapies
title_short Tracheobronchial amyloidosis managed with multimodality therapies
title_sort tracheobronchial amyloidosis managed with multimodality therapies
url https://doi.org/10.1177/1753465814524470
work_keys_str_mv AT philipsommer tracheobronchialamyloidosismanagedwithmultimodalitytherapies
AT gagankumar tracheobronchialamyloidosismanagedwithmultimodalitytherapies
AT randolphjlipchik tracheobronchialamyloidosismanagedwithmultimodalitytherapies
AT jayshiljpatel tracheobronchialamyloidosismanagedwithmultimodalitytherapies