Clinical Characteristics of Pediatric Esophagitis in Southern Iran; A Single-Center Experience
Background: We sought to determine the clinical characteristics of pediatric esophagitis in southern Iran. Methods: This cross-sectional study was conducted over a 4-year period, from 2005 to 2009, in Nemazee Hospital, a tertiary healthcare center in Shiraz, southern Iran. We consecutively included...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2013-06-01
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| Series: | Iranian Journal of Medical Sciences |
| Online Access: | http://ijms.sums.ac.ir/index.php/IJMS/article/view/296 |
| _version_ | 1828530832850026496 |
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| author | Mozhgan Zahmatkeshan Khadijesadat Najib Bita Geramizadeh Ebrahim Fallahzadeh Mahmood Haghighat Mohammad Hadi Imanieh |
| author_facet | Mozhgan Zahmatkeshan Khadijesadat Najib Bita Geramizadeh Ebrahim Fallahzadeh Mahmood Haghighat Mohammad Hadi Imanieh |
| author_sort | Mozhgan Zahmatkeshan |
| collection | DOAJ |
| description | Background: We sought to determine the clinical characteristics of pediatric esophagitis in southern Iran.
Methods: This cross-sectional study was conducted over a 4-year period, from 2005 to 2009, in Nemazee Hospital, a tertiary healthcare center in Shiraz, southern Iran. We consecutively included all pediatric patients (<18 years) who underwent endoscopy in our center and had pathology-confirmed diagnosis of esophagitis. Data regarding the patients’ demographic characteristics, comorbidities, and clinical findings were recorded using a questionnaire. All the patients underwent upper gastrointestinal endoscopy and biopsy of the esophagus, and the findings were recorded in the questionnaire.
Results: We studied 125 children, comprising 61 (48.8%) girls and 64 (51.2%) boys at a mean age of 6.6±5.5 years. Repeated vomiting was the prominent symptom in our series, with it being reported by 75 (60%) patients, followed by fever in 35 (28%). Erythema (33.6%), esophageal ulcer (11.2%), and whitish patch (8.0%) were the most common endoscopic findings, while reflux esophagitis (32.8%), chronic (6.4%) and acute esophagitis (5.6%), and candida esophagitis (5.6%) were the most common histological diagnoses. Only one (0.8%) patient was diagnosed as having eosinophilic esophagitis, aspergillosis, and graft-versus-host disease.
Conclusion: Reflux was the most common cause of esophagitis in the pediatric population of southern Iran. Contrary to previous reports, the prevalence of eosinophilic esophagitis was far less than that estimated, while the prevalence of opportunistic infections was higher secondary to post-liver transplantation immunosuppression. |
| first_indexed | 2024-12-11T22:28:54Z |
| format | Article |
| id | doaj.art-b8dd3230c7b94c169866c45cef70b263 |
| institution | Directory Open Access Journal |
| issn | 0253-0716 1735-3688 |
| language | English |
| last_indexed | 2024-12-11T22:28:54Z |
| publishDate | 2013-06-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Medical Sciences |
| spelling | doaj.art-b8dd3230c7b94c169866c45cef70b2632022-12-22T00:48:12ZengShiraz University of Medical SciencesIranian Journal of Medical Sciences0253-07161735-36882013-06-01382(1)169173Clinical Characteristics of Pediatric Esophagitis in Southern Iran; A Single-Center ExperienceMozhgan Zahmatkeshan0Khadijesadat Najib1Bita Geramizadeh2Ebrahim Fallahzadeh3Mahmood Haghighat4Mohammad Hadi Imanieh5Department of Pediatric Gastroenterology, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Pediatric, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Pathology, Shiraz Transplant Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Internal Medicine, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Pediatric Gastroenterology, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Pediatric Gastroenterology, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, IranBackground: We sought to determine the clinical characteristics of pediatric esophagitis in southern Iran. Methods: This cross-sectional study was conducted over a 4-year period, from 2005 to 2009, in Nemazee Hospital, a tertiary healthcare center in Shiraz, southern Iran. We consecutively included all pediatric patients (<18 years) who underwent endoscopy in our center and had pathology-confirmed diagnosis of esophagitis. Data regarding the patients’ demographic characteristics, comorbidities, and clinical findings were recorded using a questionnaire. All the patients underwent upper gastrointestinal endoscopy and biopsy of the esophagus, and the findings were recorded in the questionnaire. Results: We studied 125 children, comprising 61 (48.8%) girls and 64 (51.2%) boys at a mean age of 6.6±5.5 years. Repeated vomiting was the prominent symptom in our series, with it being reported by 75 (60%) patients, followed by fever in 35 (28%). Erythema (33.6%), esophageal ulcer (11.2%), and whitish patch (8.0%) were the most common endoscopic findings, while reflux esophagitis (32.8%), chronic (6.4%) and acute esophagitis (5.6%), and candida esophagitis (5.6%) were the most common histological diagnoses. Only one (0.8%) patient was diagnosed as having eosinophilic esophagitis, aspergillosis, and graft-versus-host disease. Conclusion: Reflux was the most common cause of esophagitis in the pediatric population of southern Iran. Contrary to previous reports, the prevalence of eosinophilic esophagitis was far less than that estimated, while the prevalence of opportunistic infections was higher secondary to post-liver transplantation immunosuppression.http://ijms.sums.ac.ir/index.php/IJMS/article/view/296 |
| spellingShingle | Mozhgan Zahmatkeshan Khadijesadat Najib Bita Geramizadeh Ebrahim Fallahzadeh Mahmood Haghighat Mohammad Hadi Imanieh Clinical Characteristics of Pediatric Esophagitis in Southern Iran; A Single-Center Experience Iranian Journal of Medical Sciences |
| title | Clinical Characteristics of Pediatric Esophagitis in Southern Iran; A Single-Center Experience |
| title_full | Clinical Characteristics of Pediatric Esophagitis in Southern Iran; A Single-Center Experience |
| title_fullStr | Clinical Characteristics of Pediatric Esophagitis in Southern Iran; A Single-Center Experience |
| title_full_unstemmed | Clinical Characteristics of Pediatric Esophagitis in Southern Iran; A Single-Center Experience |
| title_short | Clinical Characteristics of Pediatric Esophagitis in Southern Iran; A Single-Center Experience |
| title_sort | clinical characteristics of pediatric esophagitis in southern iran a single center experience |
| url | http://ijms.sums.ac.ir/index.php/IJMS/article/view/296 |
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