Simultaneous silencing of VEGF and KSP by siRNA cocktail inhibits proliferation and induces apoptosis of hepatocellular carcinoma Hep3B cells

BACKGROUND: Vascular endothelial growth factor (VEGF) is involved in the growth of new blood vessels that feed tumors and kinesin spindle protein (KSP) plays a critical role in mitosis involving in cell proliferation. Simultaneous silencing of VEGF and KSP, an attractive and viable approach in cance...

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Bibliographic Details
Main Authors: Chung Chinh Doan, Long Thanh Le, Son Nghia Hoang, Si Minh Do, Dong Van Le
Format: Article
Language:English
Published: BMC 2014-01-01
Series:Biological Research
Subjects:
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100064&lng=en&tlng=en

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