Mechanosensitive pore opening of a prokaryotic voltage-gated sodium channel

Mechanosensitive pore opening of a prokaryotic voltage-gated sodium channel

Voltage-gated ion channels (VGICs) orchestrate electrical activities that drive mechanical functions in contractile tissues such as the heart and gut. In turn, contractions change membrane tension and impact ion channels. VGICs are mechanosensitive, but the mechanisms of mechanosensitivity remain po...

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Bibliographic Details
Main Authors: Peter R Strege, Luke M Cowan, Constanza Alcaino, Amelia Mazzone, Christopher A Ahern, Lorin S Milescu, Gianrico Farrugia, Arthur Beyder
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-03-01
Series:eLife
Subjects:
sodium channel
mechanosensitivity
patch-clamp
electrophysiology
Online Access:https://elifesciences.org/articles/79271

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