Review of Characteristics and Analytical Methods for Determination of Thiabendazole

Thiabendazole (TBZ) is a fungicide and anthelmintic drug commonly found in food products. Due to its toxicity and potential carcinogenicity, its determination in various samples is important for public health. Different analytical methods can be used to determine the presence and concentration of TB...

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Main Authors: Mateja Budetić, Doris Kopf, Andrea Dandić, Mirela Samardžić
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/9/3926
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author Mateja Budetić
Doris Kopf
Andrea Dandić
Mirela Samardžić
author_facet Mateja Budetić
Doris Kopf
Andrea Dandić
Mirela Samardžić
author_sort Mateja Budetić
collection DOAJ
description Thiabendazole (TBZ) is a fungicide and anthelmintic drug commonly found in food products. Due to its toxicity and potential carcinogenicity, its determination in various samples is important for public health. Different analytical methods can be used to determine the presence and concentration of TBZ in samples. Liquid chromatography (LC) and its subtypes, high-performance liquid chromatography (HPLC) and ultra-high-performance liquid chromatography (UHPLC), are the most commonly used methods for TBZ determination representing 19%, 18%, and 18% of the described methods, respectively. Surface-enhanced Raman spectroscopy (SERS) and fluorimetry are two more methods widely used for TBZ determination, representing 13% and 12% of the described methods, respectively. In this review, a number of methods for TBZ determination are described, but due to their limitations, there is a high potential for the further improvement and development of each method in order to obtain a simple, precise, and accurate method that can be used for routine analysis.
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spelling doaj.art-b8e33f81a84945f191c340e126541f4e2023-11-17T23:25:19ZengMDPI AGMolecules1420-30492023-05-01289392610.3390/molecules28093926Review of Characteristics and Analytical Methods for Determination of ThiabendazoleMateja Budetić0Doris Kopf1Andrea Dandić2Mirela Samardžić3Department of Chemistry, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, CroatiaDepartment of Chemistry, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, CroatiaDepartment of Chemistry, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, CroatiaDepartment of Chemistry, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, CroatiaThiabendazole (TBZ) is a fungicide and anthelmintic drug commonly found in food products. Due to its toxicity and potential carcinogenicity, its determination in various samples is important for public health. Different analytical methods can be used to determine the presence and concentration of TBZ in samples. Liquid chromatography (LC) and its subtypes, high-performance liquid chromatography (HPLC) and ultra-high-performance liquid chromatography (UHPLC), are the most commonly used methods for TBZ determination representing 19%, 18%, and 18% of the described methods, respectively. Surface-enhanced Raman spectroscopy (SERS) and fluorimetry are two more methods widely used for TBZ determination, representing 13% and 12% of the described methods, respectively. In this review, a number of methods for TBZ determination are described, but due to their limitations, there is a high potential for the further improvement and development of each method in order to obtain a simple, precise, and accurate method that can be used for routine analysis.https://www.mdpi.com/1420-3049/28/9/3926thiabendazolepesticideanalytical methods
spellingShingle Mateja Budetić
Doris Kopf
Andrea Dandić
Mirela Samardžić
Review of Characteristics and Analytical Methods for Determination of Thiabendazole
Molecules
thiabendazole
pesticide
analytical methods
title Review of Characteristics and Analytical Methods for Determination of Thiabendazole
title_full Review of Characteristics and Analytical Methods for Determination of Thiabendazole
title_fullStr Review of Characteristics and Analytical Methods for Determination of Thiabendazole
title_full_unstemmed Review of Characteristics and Analytical Methods for Determination of Thiabendazole
title_short Review of Characteristics and Analytical Methods for Determination of Thiabendazole
title_sort review of characteristics and analytical methods for determination of thiabendazole
topic thiabendazole
pesticide
analytical methods
url https://www.mdpi.com/1420-3049/28/9/3926
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