Biomarker of early neurological deterioration in minor stroke and proximal large vessel occlusion: A pilot study

Biomarker of early neurological deterioration in minor stroke and proximal large vessel occlusion: A pilot study

BackgroundPlasma neurofilament light chain (pNFL) represents one of the scaffolding proteins of central nervous system axonal injury. The aim of this study was to evaluate pNFL as a predictive biomarker for early neurological deterioration (END) in medically managed patients with large vessel occlus...

Full description

Bibliographic Details
Main Authors:	Zhiqiang Wang, Shuai Wang, Yuxia Li, Rongyu Wang, Lianyan Jiang, Bo Zheng, Yaodan Zhang, Qingsong Wang, Jian Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-10-01
Series:	Frontiers in Neurology
Subjects:	biomarkers early neurological deterioration large vessel occlusion minor stroke neurofilament light
Online Access:	https://www.frontiersin.org/articles/10.3389/fneur.2022.1019530/full

Similar Items

Serum neurofilament light chain levels are associated with early neurological deterioration in minor ischemic stroke
by: Jie Li, et al.
Published: (2023-03-01)

Association of blood pressure parameters on early neurological deterioration in patients with mild stroke and large vessel occlusion following medical management
by: Yue Shi, et al.
Published: (2025-02-01)

Redefining Infarction Size for Small-Vessel Occlusion in Acute Ischemic Stroke: A Retrospective Case–Control Study
by: Yen-Chu Huang, et al.
Published: (2024-10-01)

The incidence of medium vessel occlusions: a population-based study
by: Michael Liu, et al.
Published: (2023-07-01)

Neurological Deterioration After Mild TBI
by: J Gordon Millichap, et al.
Published: (2014-01-01)

Endovascular Treatment for Minor Acute Ischemic Strokes With Large Vessel Occlusion
by: Rui Xue, et al.
Published: (2022-12-01)

An innovative metabolic index for insulin resistance correlates with early neurological deterioration following intravenous thrombolysis in minor acute ischemic stroke patients
by: Ling Wang, et al.
Published: (2024-09-01)

Analysis of early efficacy and safety of endovascular therapy for acute mild ischemic stroke with large vessel occlusion
by: NI Ruilong, et al.
Published: (2023-10-01)

White matter hyperintensity, parent artery steno‐occlusion, and neurological deterioration in anterior circulation single subcortical infarction patients
by: Yunhe Luo, et al.
Published: (2024-05-01)

Intra-Arterial Thrombolysis Vs. Mechanical Thrombectomy in Acute Minor Ischemic Stroke Due to Large Vessel Occlusion
by: Dapeng Sun, et al.
Published: (2022-07-01)

Large Vessel Occlusion in Patients With Minor Ischemic Stroke in a Population-Based Study. The Dijon Stroke Registry
by: Gauthier Duloquin, et al.
Published: (2022-01-01)

Early neurological deterioration with severe headache as the initial manifestation: A case report
by: Meichun Tao, MD, et al.
Published: (2025-02-01)

The effect of argatroban on early neurological deterioration and outcomes in minor ischemic stroke: preliminary findings
by: Xuehong Jin, et al.
Published: (2024-03-01)

Assessing the Efficacy of Mechanical Thrombectomy in Patients with an NIHSS < 6 Presenting with Proximal Middle Cerebral Artery Vessel Occlusion as Compared to Best Medical Management
by: Vivek Srikar Yedavalli, et al.
Published: (2023-01-01)

Prediction of Neurological Deterioration After Intracerebral Hemorrhage: The SIGNALS Score
by: Quanwei He, et al.
Published: (2022-08-01)

Effects of edaravone dexborneol on neurological function and serum inflammatory factor levels in patients with acute anterior circulation large vessel occlusion stroke
by: Hu Xiaohong, et al.
Published: (2023-10-01)

Mild Luminal Stenosis of Parent Artery and Neurologic Deterioration After Acute Lacunar Stroke
by: Dixon Yang, et al.
Published: (2022-01-01)

Imaging biomarker associated with early neurological deterioration in isolated pontine infarction
by: Xiaowei Song, et al.
Published: (2024-12-01)

Predictive Factors of Early Neurologic Deterioration in Isolated Pontine Infarction
by: Shan Gao, et al.
Published: (2025-01-01)

Predictors of Neurological Deterioration during Admission for Patients with Cerebellar Strokes
by: Thanyalak Amornpojnimman, et al.
Published: (2022-01-01)

Prospective study on relationship between legumain and early neurological deterioration in patients with acute large artery atherosclerotic stroke
by: RONG Tianyi, HUA Yun, CHEN Deyan, HE Min
Published: (2021-04-01)

Impacts of stress hyperglycemia ratio on early neurological deterioration and functional outcome after endovascular treatment in patients with acute ischemic stroke
by: Zheng Dai, et al.
Published: (2023-01-01)

Association between impaired brachial flow-mediated dilation and early neurological deterioration in acute ischemic stroke: a retrospective analysis
by: Sang Hee Ha, et al.
Published: (2025-02-01)

“Is tirofiban the silver bullet for early neurological deterioration in stroke?”
by: Asad Gul Rao
Published: (2024-06-01)

Association of triglyceride-glucose index with early neurological deterioration events in patients with acute ischemic stroke
by: Jia Wang, et al.
Published: (2023-05-01)

Predictive values of systemic inflammatory responses index in early neurological deterioration in patients with acute ischemic stroke
by: Jia Wang, et al.
Published: (2022-05-01)

Malnutrition and the Risk of Early Neurological Deterioration in Elderly Patients with Acute Ischemic Stroke
by: Bao Y, et al.
Published: (2022-08-01)

Predictors of early neurological deterioration in patients with acute ischemic stroke
by: Yang Zhou, et al.
Published: (2024-08-01)

Neurological Deterioration in Intracerebral Hemorrhage: Can We Predict It, and What Would We Do If We Could?
by: Qi Li, et al.
Published: (2022-08-01)

Clinical and imaging risk factors for early neurological deterioration and long-term neurological disability in patients with single subcortical small infarction
by: Xiao Feng, et al.
Published: (2025-02-01)

Serum Lipoprotein(a) as Predictive Factor for Early Neurological Deterioration of Acute Ischemic Stroke After Thrombolysis
by: Wang R, et al.
Published: (2024-08-01)

A Nomogram Incorporating Intracranial Atherosclerosis Score for Predicting Early Neurological Deterioration in Minor Stroke Patients With Type 2 Diabetes Mellitus
by: Shang J, et al.
Published: (2025-02-01)

Post-thrombolysis early neurological deterioration occurs with or without hemorrhagic transformation in acute cerebral infarction: risk factors, prediction model and prognosis
by: Mengzhi Jin, et al.
Published: (2023-05-01)

Early Neurologic Deterioration and Efficacy of Dual Antiplatelet in Anterior Versus Posterior Circulation Stroke
by: Yu Cui, et al.
Published: (2025-02-01)

The neutrophil-to-lymphocyte ratio is an important indicator correlated to early neurological deterioration in single subcortical infarct patients with diabetes
by: Lijun Fang, et al.
Published: (2022-10-01)

Effect of Nurse's detection of neurological deterioration on the prognosis of patients with acute cerebral infarction
by: Jung-Hee Han, et al.
Published: (2024-06-01)

RapidAI Compared With Human Readers of Acute Stroke Imaging for Detection of Intracranial Vessel Occlusion
by: Lee‐Anne Slater, et al.
Published: (2024-03-01)

Serum uric acid to serum creatinine ratio predicts neurological deterioration in branch atheromatous disease
by: Yinglin Liu, et al.
Published: (2023-01-01)

Intravenous thrombolysis prevents neurological deterioration in patients with acute pontine infarction
by: Zhenxiao Chai, et al.
Published: (2025-01-01)

Increased serum alkaline phosphatase and early neurological deterioration in patients with atherothrombotic brain infarction attributable to intracranial atherosclerosis
by: Toshiyuki Uehara, et al.
Published: (2020-09-01)