Virology analysis in HCV genotype 1-infected patients treated with the combination of simeprevir and TMC647055/ritonavir, with and without ribavirin, and JNJ-56914845

Virology analysis in HCV genotype 1-infected patients treated with the combination of simeprevir and TMC647055/ritonavir, with and without ribavirin, and JNJ-56914845

Abstract Background In study TMC647055HPC2001, a 3-direct-acting-antiviral (DAA) regimen combining NS3/4A protease inhibitor simeprevir (SMV), non-nucleoside NS5B inhibitor TMC647055/ritonavir (RTV) and NS5A inhibitor JNJ-56914845 resulted in high sustained virologic response 12 weeks after actual e...

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Bibliographic Details
Main Authors: Leen Vijgen, Kim Thys, An Vandebosch, Pieter Van Remoortere, René Verloes, Sandra De Meyer
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Virology Journal
Subjects:
Hepatitis C virus
Genotype 1
Simeprevir
TMC647055/ritonavir
JNJ-56914845
Online Access:http://link.springer.com/article/10.1186/s12985-017-0760-2

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