Colposcopy Accuracy and Diagnostic Performance: A Quality Control and Quality Assurance Survey in Italian Tertiary-Level Teaching and Academic Institutions—The Italian Society of Colposcopy and Cervico-Vaginal Pathology (SICPCV)
Quality Control (QC) and Quality Assurance (QA) principles are essential for effective cervical cancer prevention. Being a crucial diagnostic step, colposcopy’s sensitivity and specificity improvements are strongly advocated worldwide since inter- and intra-observer differences are the main limiting...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-05-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/11/1906 |
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| author | Massimo Origoni Francesco Cantatore Francesco Sopracordevole Nicolò Clemente Arsenio Spinillo Barbara Gardella Rosa De Vincenzo Caterina Ricci Fabio Landoni Maria Letizia Di Meo Andrea Ciavattini Jacopo Di Giuseppe Eleonora Preti Anna Daniela Iacobone Carmine Carriero Miriam Dellino Massimo Capodanno Antonino Perino Cesare Miglioli Luca Insolia Maggiorino Barbero Massimo Candiani |
| author_facet | Massimo Origoni Francesco Cantatore Francesco Sopracordevole Nicolò Clemente Arsenio Spinillo Barbara Gardella Rosa De Vincenzo Caterina Ricci Fabio Landoni Maria Letizia Di Meo Andrea Ciavattini Jacopo Di Giuseppe Eleonora Preti Anna Daniela Iacobone Carmine Carriero Miriam Dellino Massimo Capodanno Antonino Perino Cesare Miglioli Luca Insolia Maggiorino Barbero Massimo Candiani |
| author_sort | Massimo Origoni |
| collection | DOAJ |
| description | Quality Control (QC) and Quality Assurance (QA) principles are essential for effective cervical cancer prevention. Being a crucial diagnostic step, colposcopy’s sensitivity and specificity improvements are strongly advocated worldwide since inter- and intra-observer differences are the main limiting factors. The objective of the present study was the evaluation of colposcopy accuracy through the results of a QC/QA assessment from a survey in Italian tertiary-level academic and teaching hospitals. A web-based, user-friendly platform based on 100 colposcopic digital images was forwarded to colposcopists with different levels of experience. Seventy-three participants were asked to identify colposcopic patterns, provide personal impressions, and indicate the correct clinical practice. The data were correlated with a panel of experts’ evaluation and with the clinical/pathological data of the cases. Overall sensitivity and specificity with the threshold of CIN2+ accounted for 73.7% and 87.7%, respectively, with minor differences between senior and junior candidates. Identification and interpretation of colposcopic patterns showed full agreement with the experts’ panel, ranging from 50% to 82%, in some instances with better results from junior colposcopists. Colposcopic impressions correlated with a 20% underestimation of CIN2+ lesions, with no differences linked to level of experience. Our results demonstrate the good diagnostic performance of colposcopy and the need for improving accuracy through QC assessments and adhesion to standard requirements and recommendations. |
| first_indexed | 2024-03-11T03:09:51Z |
| format | Article |
| id | doaj.art-b8ecaae196a24d21804205005eacd764 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-11T03:09:51Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-b8ecaae196a24d21804205005eacd7642023-11-18T07:42:41ZengMDPI AGDiagnostics2075-44182023-05-011311190610.3390/diagnostics13111906Colposcopy Accuracy and Diagnostic Performance: A Quality Control and Quality Assurance Survey in Italian Tertiary-Level Teaching and Academic Institutions—The Italian Society of Colposcopy and Cervico-Vaginal Pathology (SICPCV)Massimo Origoni0Francesco Cantatore1Francesco Sopracordevole2Nicolò Clemente3Arsenio Spinillo4Barbara Gardella5Rosa De Vincenzo6Caterina Ricci7Fabio Landoni8Maria Letizia Di Meo9Andrea Ciavattini10Jacopo Di Giuseppe11Eleonora Preti12Anna Daniela Iacobone13Carmine Carriero14Miriam Dellino15Massimo Capodanno16Antonino Perino17Cesare Miglioli18Luca Insolia19Maggiorino Barbero20Massimo Candiani21Department of Obstetrics & Gynecology, IRCCS Ospedale San Raffaele, Vita Salute San Raffaele University School of Medicine, 20132 Milan, ItalyDepartment of Obstetrics & Gynecology, IRCCS Ospedale San Raffaele, Vita Salute San Raffaele University School of Medicine, 20132 Milan, ItalyGynecological Oncology Unit, IRCCS Oncological Referral Center (CRO), National Cancer Institute, 33081 Aviano, ItalyGynecological Oncology Unit, IRCCS Oncological Referral Center (CRO), National Cancer Institute, 33081 Aviano, ItalyDepartment of Obstetrics & Gynecology, IRCCS Policlinico San Matteo, University of Pavia, 27100 Pavia, ItalyDepartment of Obstetrics & Gynecology, IRCCS Policlinico San Matteo, University of Pavia, 27100 Pavia, ItalyGynecological Oncology Unit, Department of Woman and Child Health and Public Health, IRCCS Policlinico Universitario A. Gemelli, 00168 Rome, ItalyDepartment of Health Sciences and Public Health, Catholic University of the Sacred Hearth, 00168 Rome, ItalyDepartment of Medicine and Surgery, University of Milano Bicocca, Clinic of Obstetrics and Gynecology, IRCCS San Gerardo dei Tintori, 20900 Monza, ItalyDepartment of Medicine and Surgery, University of Milano Bicocca, Clinic of Obstetrics and Gynecology, IRCCS San Gerardo dei Tintori, 20900 Monza, ItalyGynecologic Section, Department of Odontostomatological and Specialized Clinical Sciences, Marche Polytechnic University, 60123 Ancona, ItalyGynecologic Section, Department of Odontostomatological and Specialized Clinical Sciences, Marche Polytechnic University, 60123 Ancona, ItalyPreventive Gynecology Unit, IRCCS European Institute of Oncology (IEO), 20141 Milan, ItalyPreventive Gynecology Unit, IRCCS European Institute of Oncology (IEO), 20141 Milan, ItalyInterdisciplinary Department of Medicine, University of Bari Aldo Moro, 70121 Bari, ItalyInterdisciplinary Department of Medicine, University of Bari Aldo Moro, 70121 Bari, ItalyDepartment of Obstetrics and Gynecology, University of Napoli, 80138 Naples, ItalyDepartment of Obstetrics and Gynecology, University of Palermo, 90146 Palermo, ItalyResearch Center for Statistics, University of Geneva, 1201 Geneva, SwitzerlandResearch Center for Statistics, University of Geneva, 1201 Geneva, SwitzerlandDepartment of Obstetrics and Gynecology, Azienda Sanitaria Locale di Asti, 14100 Asti, ItalyDepartment of Obstetrics & Gynecology, IRCCS Ospedale San Raffaele, Vita Salute San Raffaele University School of Medicine, 20132 Milan, ItalyQuality Control (QC) and Quality Assurance (QA) principles are essential for effective cervical cancer prevention. Being a crucial diagnostic step, colposcopy’s sensitivity and specificity improvements are strongly advocated worldwide since inter- and intra-observer differences are the main limiting factors. The objective of the present study was the evaluation of colposcopy accuracy through the results of a QC/QA assessment from a survey in Italian tertiary-level academic and teaching hospitals. A web-based, user-friendly platform based on 100 colposcopic digital images was forwarded to colposcopists with different levels of experience. Seventy-three participants were asked to identify colposcopic patterns, provide personal impressions, and indicate the correct clinical practice. The data were correlated with a panel of experts’ evaluation and with the clinical/pathological data of the cases. Overall sensitivity and specificity with the threshold of CIN2+ accounted for 73.7% and 87.7%, respectively, with minor differences between senior and junior candidates. Identification and interpretation of colposcopic patterns showed full agreement with the experts’ panel, ranging from 50% to 82%, in some instances with better results from junior colposcopists. Colposcopic impressions correlated with a 20% underestimation of CIN2+ lesions, with no differences linked to level of experience. Our results demonstrate the good diagnostic performance of colposcopy and the need for improving accuracy through QC assessments and adhesion to standard requirements and recommendations.https://www.mdpi.com/2075-4418/13/11/1906colposcopyQCQAcolposcopy sensitivitydiagnostic accuracycervical cancer prevention |
| spellingShingle | Massimo Origoni Francesco Cantatore Francesco Sopracordevole Nicolò Clemente Arsenio Spinillo Barbara Gardella Rosa De Vincenzo Caterina Ricci Fabio Landoni Maria Letizia Di Meo Andrea Ciavattini Jacopo Di Giuseppe Eleonora Preti Anna Daniela Iacobone Carmine Carriero Miriam Dellino Massimo Capodanno Antonino Perino Cesare Miglioli Luca Insolia Maggiorino Barbero Massimo Candiani Colposcopy Accuracy and Diagnostic Performance: A Quality Control and Quality Assurance Survey in Italian Tertiary-Level Teaching and Academic Institutions—The Italian Society of Colposcopy and Cervico-Vaginal Pathology (SICPCV) Diagnostics colposcopy QC QA colposcopy sensitivity diagnostic accuracy cervical cancer prevention |
| title | Colposcopy Accuracy and Diagnostic Performance: A Quality Control and Quality Assurance Survey in Italian Tertiary-Level Teaching and Academic Institutions—The Italian Society of Colposcopy and Cervico-Vaginal Pathology (SICPCV) |
| title_full | Colposcopy Accuracy and Diagnostic Performance: A Quality Control and Quality Assurance Survey in Italian Tertiary-Level Teaching and Academic Institutions—The Italian Society of Colposcopy and Cervico-Vaginal Pathology (SICPCV) |
| title_fullStr | Colposcopy Accuracy and Diagnostic Performance: A Quality Control and Quality Assurance Survey in Italian Tertiary-Level Teaching and Academic Institutions—The Italian Society of Colposcopy and Cervico-Vaginal Pathology (SICPCV) |
| title_full_unstemmed | Colposcopy Accuracy and Diagnostic Performance: A Quality Control and Quality Assurance Survey in Italian Tertiary-Level Teaching and Academic Institutions—The Italian Society of Colposcopy and Cervico-Vaginal Pathology (SICPCV) |
| title_short | Colposcopy Accuracy and Diagnostic Performance: A Quality Control and Quality Assurance Survey in Italian Tertiary-Level Teaching and Academic Institutions—The Italian Society of Colposcopy and Cervico-Vaginal Pathology (SICPCV) |
| title_sort | colposcopy accuracy and diagnostic performance a quality control and quality assurance survey in italian tertiary level teaching and academic institutions the italian society of colposcopy and cervico vaginal pathology sicpcv |
| topic | colposcopy QC QA colposcopy sensitivity diagnostic accuracy cervical cancer prevention |
| url | https://www.mdpi.com/2075-4418/13/11/1906 |
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