Type-I Interferon responses: From Friend to Foe in the Battle against Chronic Viral Infection

Type-I Interferon responses: From Friend to Foe in the Battle against Chronic Viral Infection

Type I interferons (IFN-I) have long been heralded as key contributors to effective antiviral responses. More widely understood in the context of acute viral infection, the role of this pleiotropic cytokine has been characterized as triggering antiviral states in cells and potentiating adaptive immu...

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Bibliographic Details
Main Authors: Armstrong Murira, Alain Lamarre
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Immunology
Subjects:
Immunoregulation
immunopathology
Type-I interferon
Chronic viral infection
IFNAR
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00609/full

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