TIMP-2 inhibits metastasis and predicts prognosis of colorectal cancer via regulating MMP-9

TIMP-2 inhibits metastasis and predicts prognosis of colorectal cancer via regulating MMP-9

Colorectal cancer has a common cause of morbidity and mortality. Therefore, it is urgent to detect reliable biomarkers to predict prognosis in CRC. Here, we determined the expression of TIMP-2 and MMP-9 in a  CRC tissue microarray by immunohistochemistry. We found that lower TIMP-2 or/and higher MMP...

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Bibliographic Details
Main Authors: Weimin Wang, Dan Li, Liangliang Xiang, Mengying Lv, Li Tao, Tengyang Ni, Jianliang Deng, Xiancheng Gu, Sunagawa Masatara, Yanqing Liu, Yan Zhou
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Cell Adhesion & Migration
Subjects:
crc
timp-2
mmp-9
prognosis
metastasis
Online Access:http://dx.doi.org/10.1080/19336918.2019.1639303

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