End-to-End Continuous Small-Scale Drug Substance Manufacturing: From a Continuous In Situ Nucleator to Free-Flowing Crystalline Particles

End-to-End Continuous Small-Scale Drug Substance Manufacturing: From a Continuous In Situ Nucleator to Free-Flowing Crystalline Particles

In the evolving landscape of pharmaceutical manufacturing, a comprehensive continuous production process is being crafted for the small-scale production of active pharmaceutical ingredients. This study focuses on continuous crystallization with separate nucleation and crystal growth units, as well a...

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Bibliographic Details
Main Authors: Anne Cathrine Kufner, Marc Meier, Kerstin Wohlgemuth
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Crystals
Subjects:
continuous manufacturing
continuous nucleation
3D printing
continuous downstream
small-scale production
high-quality products
Online Access:https://www.mdpi.com/2073-4352/13/12/1675

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