Microfluidic Chip with Fiber-Tip Sensors for Synchronously Monitoring Concentration and Temperature of Glucose Solutions
Monitoring the properties of fluids in microfluidic chips often requires complex open-space optics technology and expensive equipment. In this work, we introduce dual-parameter optical sensors with fiber tips into the microfluidic chip. Multiple sensors were distributed in each channel of the chip,...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-02-01
|
| Series: | Sensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1424-8220/23/5/2478 |
| _version_ | 1797614394821050368 |
|---|---|
| author | Jian Qu Yi Liu Yan Li Jinjian Li Songhe Meng |
| author_facet | Jian Qu Yi Liu Yan Li Jinjian Li Songhe Meng |
| author_sort | Jian Qu |
| collection | DOAJ |
| description | Monitoring the properties of fluids in microfluidic chips often requires complex open-space optics technology and expensive equipment. In this work, we introduce dual-parameter optical sensors with fiber tips into the microfluidic chip. Multiple sensors were distributed in each channel of the chip, which enabled the real-time monitoring of the concentration and temperature of the microfluidics. The temperature sensitivity and glucose concentration sensitivity could reach 314 pm/°C and −0.678 dB/(g/L), respectively. The hemispherical probe hardly affected the microfluidic flow field. The integrated technology combined the optical fiber sensor with the microfluidic chip and was low cost with high performance. Therefore, we believe that the proposed microfluidic chip integrated with the optical sensor is beneficial for drug discovery, pathological research and material science investigation. The integrated technology has great application potential for micro total analysis systems (μ-TAS). |
| first_indexed | 2024-03-11T07:11:49Z |
| format | Article |
| id | doaj.art-b8fc05ebe9de412c97fdba8aa9900961 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-11T07:11:49Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-b8fc05ebe9de412c97fdba8aa99009612023-11-17T08:35:20ZengMDPI AGSensors1424-82202023-02-01235247810.3390/s23052478Microfluidic Chip with Fiber-Tip Sensors for Synchronously Monitoring Concentration and Temperature of Glucose SolutionsJian Qu0Yi Liu1Yan Li2Jinjian Li3Songhe Meng4Center for Composite Materials, Harbin Institute of Technology, Harbin 150001, ChinaSchool of Physics, Harbin Institute of Technology, Harbin 150001, ChinaSchool of Physics, Harbin Institute of Technology, Harbin 150001, ChinaSchool of Physics, Harbin Institute of Technology, Harbin 150001, ChinaCenter for Composite Materials, Harbin Institute of Technology, Harbin 150001, ChinaMonitoring the properties of fluids in microfluidic chips often requires complex open-space optics technology and expensive equipment. In this work, we introduce dual-parameter optical sensors with fiber tips into the microfluidic chip. Multiple sensors were distributed in each channel of the chip, which enabled the real-time monitoring of the concentration and temperature of the microfluidics. The temperature sensitivity and glucose concentration sensitivity could reach 314 pm/°C and −0.678 dB/(g/L), respectively. The hemispherical probe hardly affected the microfluidic flow field. The integrated technology combined the optical fiber sensor with the microfluidic chip and was low cost with high performance. Therefore, we believe that the proposed microfluidic chip integrated with the optical sensor is beneficial for drug discovery, pathological research and material science investigation. The integrated technology has great application potential for micro total analysis systems (μ-TAS).https://www.mdpi.com/1424-8220/23/5/2478microfluidic chipsfiber-tip sensordual parameter sensor |
| spellingShingle | Jian Qu Yi Liu Yan Li Jinjian Li Songhe Meng Microfluidic Chip with Fiber-Tip Sensors for Synchronously Monitoring Concentration and Temperature of Glucose Solutions Sensors microfluidic chips fiber-tip sensor dual parameter sensor |
| title | Microfluidic Chip with Fiber-Tip Sensors for Synchronously Monitoring Concentration and Temperature of Glucose Solutions |
| title_full | Microfluidic Chip with Fiber-Tip Sensors for Synchronously Monitoring Concentration and Temperature of Glucose Solutions |
| title_fullStr | Microfluidic Chip with Fiber-Tip Sensors for Synchronously Monitoring Concentration and Temperature of Glucose Solutions |
| title_full_unstemmed | Microfluidic Chip with Fiber-Tip Sensors for Synchronously Monitoring Concentration and Temperature of Glucose Solutions |
| title_short | Microfluidic Chip with Fiber-Tip Sensors for Synchronously Monitoring Concentration and Temperature of Glucose Solutions |
| title_sort | microfluidic chip with fiber tip sensors for synchronously monitoring concentration and temperature of glucose solutions |
| topic | microfluidic chips fiber-tip sensor dual parameter sensor |
| url | https://www.mdpi.com/1424-8220/23/5/2478 |
| work_keys_str_mv | AT jianqu microfluidicchipwithfibertipsensorsforsynchronouslymonitoringconcentrationandtemperatureofglucosesolutions AT yiliu microfluidicchipwithfibertipsensorsforsynchronouslymonitoringconcentrationandtemperatureofglucosesolutions AT yanli microfluidicchipwithfibertipsensorsforsynchronouslymonitoringconcentrationandtemperatureofglucosesolutions AT jinjianli microfluidicchipwithfibertipsensorsforsynchronouslymonitoringconcentrationandtemperatureofglucosesolutions AT songhemeng microfluidicchipwithfibertipsensorsforsynchronouslymonitoringconcentrationandtemperatureofglucosesolutions |