Hyperprogression of cutaneous T cell lymphoma after anti–PD-1 treatment

Hyperprogression of cutaneous T cell lymphoma after anti–PD-1 treatment

BACKGROUND Immune checkpoint blockade is an emerging treatment for T cell non-Hodgkin’s lymphoma (T-NHL), but some patients with T-NHL have experienced hyperprogression with undetermined mechanisms upon anti–PD-1 therapy.METHODS Single-cell RNA-Seq, whole-genome sequencing, whole-exome sequencing, a...

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Main Authors: Yumei Gao, Simeng Hu, Ruoyan Li, Shanzhao Jin, Fengjie Liu, Xiangjun Liu, Yingyi Li, Yicen Yan, Weiping Liu, Jifang Gong, Shuxia Yang, Ping Tu, Lin Shen, Fan Bai, Yang Wang
Format: Article
Language:English
Published: American Society for Clinical investigation 2023-02-01
Series:JCI Insight
Subjects:
Oncology
Online Access:https://doi.org/10.1172/jci.insight.164793

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