Wall Shear Stress Measurement in Carotid Artery Phantoms with Variation in Degree of Stenosis Using Plane Wave Vector Doppler
Wall shear stress (WSS) plays an important role in the formation, growth, and rupture of atherosclerotic plaques in arteries. This study measured WSS in diseased carotid artery phantoms with degrees of stenosis varying from 0 to 60% with both steady and pulsatile flow. Experiments were performed usi...
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| Format: | Article |
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MDPI AG
2023-01-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/13/1/617 |
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| author | Ke Yang Peter R. Hoskins George A. Corner Chunming Xia Zhihong Huang |
| author_facet | Ke Yang Peter R. Hoskins George A. Corner Chunming Xia Zhihong Huang |
| author_sort | Ke Yang |
| collection | DOAJ |
| description | Wall shear stress (WSS) plays an important role in the formation, growth, and rupture of atherosclerotic plaques in arteries. This study measured WSS in diseased carotid artery phantoms with degrees of stenosis varying from 0 to 60% with both steady and pulsatile flow. Experiments were performed using in silico and real flow phantoms. Blood velocities were estimated using plane wave (PW) vector Doppler. Wall shear stress was then estimated from the velocity gradient near the wall multiplied by the viscosity of a blood-mimicking fluid. The estimated WSS using the in silico phantom agreed within 10% of the ground-truth values (root-mean-square error). The phantom experiment showed that the mean WSS and maximum WSS increased with the increasing degree of stenosis. The simulation and experiment results provide the necessary validation data to give confidence in WSS measurements in patients using the PW vector Doppler technique. |
| first_indexed | 2024-03-11T10:07:09Z |
| format | Article |
| id | doaj.art-b904baf1813d4ddc988e5ed4277969ae |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-11T10:07:09Z |
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| spelling | doaj.art-b904baf1813d4ddc988e5ed4277969ae2023-11-16T14:59:24ZengMDPI AGApplied Sciences2076-34172023-01-0113161710.3390/app13010617Wall Shear Stress Measurement in Carotid Artery Phantoms with Variation in Degree of Stenosis Using Plane Wave Vector DopplerKe Yang0Peter R. Hoskins1George A. Corner2Chunming Xia3Zhihong Huang4School of Mechanical and Power Engineering, East China University of Science and Technology, Shanghai 200237, ChinaSchool of Science and Engineering, University of Dundee, Dundee DD1 4HN, UKSchool of Science and Engineering, University of Dundee, Dundee DD1 4HN, UKSchool of Mechanical and Power Engineering, East China University of Science and Technology, Shanghai 200237, ChinaSchool of Science and Engineering, University of Dundee, Dundee DD1 4HN, UKWall shear stress (WSS) plays an important role in the formation, growth, and rupture of atherosclerotic plaques in arteries. This study measured WSS in diseased carotid artery phantoms with degrees of stenosis varying from 0 to 60% with both steady and pulsatile flow. Experiments were performed using in silico and real flow phantoms. Blood velocities were estimated using plane wave (PW) vector Doppler. Wall shear stress was then estimated from the velocity gradient near the wall multiplied by the viscosity of a blood-mimicking fluid. The estimated WSS using the in silico phantom agreed within 10% of the ground-truth values (root-mean-square error). The phantom experiment showed that the mean WSS and maximum WSS increased with the increasing degree of stenosis. The simulation and experiment results provide the necessary validation data to give confidence in WSS measurements in patients using the PW vector Doppler technique.https://www.mdpi.com/2076-3417/13/1/617wall shear stressstenosis phantomplane wavevector Doppler |
| spellingShingle | Ke Yang Peter R. Hoskins George A. Corner Chunming Xia Zhihong Huang Wall Shear Stress Measurement in Carotid Artery Phantoms with Variation in Degree of Stenosis Using Plane Wave Vector Doppler Applied Sciences wall shear stress stenosis phantom plane wave vector Doppler |
| title | Wall Shear Stress Measurement in Carotid Artery Phantoms with Variation in Degree of Stenosis Using Plane Wave Vector Doppler |
| title_full | Wall Shear Stress Measurement in Carotid Artery Phantoms with Variation in Degree of Stenosis Using Plane Wave Vector Doppler |
| title_fullStr | Wall Shear Stress Measurement in Carotid Artery Phantoms with Variation in Degree of Stenosis Using Plane Wave Vector Doppler |
| title_full_unstemmed | Wall Shear Stress Measurement in Carotid Artery Phantoms with Variation in Degree of Stenosis Using Plane Wave Vector Doppler |
| title_short | Wall Shear Stress Measurement in Carotid Artery Phantoms with Variation in Degree of Stenosis Using Plane Wave Vector Doppler |
| title_sort | wall shear stress measurement in carotid artery phantoms with variation in degree of stenosis using plane wave vector doppler |
| topic | wall shear stress stenosis phantom plane wave vector Doppler |
| url | https://www.mdpi.com/2076-3417/13/1/617 |
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