O.I. Glazova and Her Contribution to the Development of Domestic Emergency Clinical Toxicology
The biography of Olga Ivanovna Glazova, doctor of medical sciences, honored doctor of the RSFSR, member of the Scientific Council of the N.V. Sklifosovsky Research Institute, is an example of an exceptionally successful diversification of scientific activity, both in the field of cardiology and clin...
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| Format: | Article |
| Language: | Russian |
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Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department
2020-01-01
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| Series: | Неотложная медицинская помощь |
| Subjects: | |
| Online Access: | https://www.jnmp.ru/jour/article/view/756 |
| _version_ | 1797758118793314304 |
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| author | Y. S. Goldfarb S. A. Kabanova M. M. Potskhveriya V. I. Sleptsov |
| author_facet | Y. S. Goldfarb S. A. Kabanova M. M. Potskhveriya V. I. Sleptsov |
| author_sort | Y. S. Goldfarb |
| collection | DOAJ |
| description | The biography of Olga Ivanovna Glazova, doctor of medical sciences, honored doctor of the RSFSR, member of the Scientific Council of the N.V. Sklifosovsky Research Institute, is an example of an exceptionally successful diversification of scientific activity, both in the field of cardiology and clinical toxicology, which is the new direction of Russian medicine.There are suggestions in the works of O.I. Glazova similar to modern ideas of acute poisonings (AP), as confirmed by later publications in this field. The pathogenetic approach to the study of AP was considered by O.I. Glazova from the perspective of the teachings of I.P. Pavlov about the body as a single entity, and the action of the poison hypothetically dependent on its concentration in the blood. She emphasized the need for the early removal of poison from the body to prevent the adverse course of poisoning. The role of antidote therapy as an example of a detoxification approach to the treatment of AP was noted, while antidotes for parenteral administration were recommended in order to increase the effectiveness of detoxification.Some thoughts were expressed about the dependence of the toxic effects of poisons on physical and chemical properties, as well as similar ideas about the quantitative measure of poisoning, selective and situational toxicity, the presence of concentration, space and temporal factors in the pathogenesis of poisoning. The systematization of the AP was presented.Thus, O.I. Glazova made a significant contribution to the study of AP thanks to her enthusiasm, constant creative eagerness and high professional competence, which contributed to a significant growth the role of representatives of the emergency medical clinic in AP treatment, and in turn positively affected the regularity and quality of further research in this area.Authors declare lack of the conflicts of interests. |
| first_indexed | 2024-03-12T18:25:25Z |
| format | Article |
| id | doaj.art-b906cc3bab8d41e8aceaef980abd41cc |
| institution | Directory Open Access Journal |
| issn | 2223-9022 2541-8017 |
| language | Russian |
| last_indexed | 2024-03-12T18:25:25Z |
| publishDate | 2020-01-01 |
| publisher | Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department |
| record_format | Article |
| series | Неотложная медицинская помощь |
| spelling | doaj.art-b906cc3bab8d41e8aceaef980abd41cc2023-08-02T08:34:44ZrusSklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare DepartmentНеотложная медицинская помощь2223-90222541-80172020-01-018446647310.23934/2223-9022-2019-8-4-466-473559O.I. Glazova and Her Contribution to the Development of Domestic Emergency Clinical ToxicologyY. S. Goldfarb0S. A. Kabanova1M. M. Potskhveriya2V. I. Sleptsov3N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow health Department; Russian Medical Academy of Postgraduate Education of the Ministry of health of Russian FederationN.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow health Department; A.I. Yevdokimov Moscow State university of Medicine and Dentistry of the Ministry of health of Russian FederationN.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow health Department; Russian Medical Academy of Postgraduate Education of the Ministry of health of Russian FederationN.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow health DepartmentThe biography of Olga Ivanovna Glazova, doctor of medical sciences, honored doctor of the RSFSR, member of the Scientific Council of the N.V. Sklifosovsky Research Institute, is an example of an exceptionally successful diversification of scientific activity, both in the field of cardiology and clinical toxicology, which is the new direction of Russian medicine.There are suggestions in the works of O.I. Glazova similar to modern ideas of acute poisonings (AP), as confirmed by later publications in this field. The pathogenetic approach to the study of AP was considered by O.I. Glazova from the perspective of the teachings of I.P. Pavlov about the body as a single entity, and the action of the poison hypothetically dependent on its concentration in the blood. She emphasized the need for the early removal of poison from the body to prevent the adverse course of poisoning. The role of antidote therapy as an example of a detoxification approach to the treatment of AP was noted, while antidotes for parenteral administration were recommended in order to increase the effectiveness of detoxification.Some thoughts were expressed about the dependence of the toxic effects of poisons on physical and chemical properties, as well as similar ideas about the quantitative measure of poisoning, selective and situational toxicity, the presence of concentration, space and temporal factors in the pathogenesis of poisoning. The systematization of the AP was presented.Thus, O.I. Glazova made a significant contribution to the study of AP thanks to her enthusiasm, constant creative eagerness and high professional competence, which contributed to a significant growth the role of representatives of the emergency medical clinic in AP treatment, and in turn positively affected the regularity and quality of further research in this area.Authors declare lack of the conflicts of interests.https://www.jnmp.ru/jour/article/view/756foreign body in the esophagusthoracotomymediastinitisrepeated toracotomytetrahydrocannabinol acid |
| spellingShingle | Y. S. Goldfarb S. A. Kabanova M. M. Potskhveriya V. I. Sleptsov O.I. Glazova and Her Contribution to the Development of Domestic Emergency Clinical Toxicology Неотложная медицинская помощь foreign body in the esophagus thoracotomy mediastinitis repeated toracotomy tetrahydrocannabinol acid |
| title | O.I. Glazova and Her Contribution to the Development of Domestic Emergency Clinical Toxicology |
| title_full | O.I. Glazova and Her Contribution to the Development of Domestic Emergency Clinical Toxicology |
| title_fullStr | O.I. Glazova and Her Contribution to the Development of Domestic Emergency Clinical Toxicology |
| title_full_unstemmed | O.I. Glazova and Her Contribution to the Development of Domestic Emergency Clinical Toxicology |
| title_short | O.I. Glazova and Her Contribution to the Development of Domestic Emergency Clinical Toxicology |
| title_sort | o i glazova and her contribution to the development of domestic emergency clinical toxicology |
| topic | foreign body in the esophagus thoracotomy mediastinitis repeated toracotomy tetrahydrocannabinol acid |
| url | https://www.jnmp.ru/jour/article/view/756 |
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