Prevalence of Syphilis among People living with HIV (PLHIV) attending a tertiary care hospital in coastal south India

Background: Syphilis and HIV are both transmitted sexually so people can be infected with both diseases. Co-infection of syphilis and HIV alters the course of both the diseases. Venereal disease research laboratory (VDRL) test is a non-treponemal test, used commonly in Antiretroviral Therapy Centres...

Full description

Bibliographic Details
Main Author: Deepak Madi
Format: Article
Language:English
Published: Manipal College of Medical Sciences, Pokhara 2015-05-01
Series:Asian Journal of Medical Sciences
Subjects:
Online Access:https://www.nepjol.info/index.php/AJMS/article/view/11623
_version_ 1818119936030015488
author Deepak Madi
author_facet Deepak Madi
author_sort Deepak Madi
collection DOAJ
description Background: Syphilis and HIV are both transmitted sexually so people can be infected with both diseases. Co-infection of syphilis and HIV alters the course of both the diseases. Venereal disease research laboratory (VDRL) test is a non-treponemal test, used commonly in Antiretroviral Therapy Centres (ART) in India to detect syphilis. The aim of our study was to determine the prevalence of syphilis in HIV-infected patients attending a tertiary care hospital using VDRL test. Materials and Methods: Using a cross-sectional study design 113 HIV positive patients were included. VDRL test was used to screen for syphilis. The collected data was analyzed using SPSS version 11.5. Results: Among the 113 patients screened 69(61%) were males and 44(39%) were females. Majority of the patients had acquired the disease through heterosexual transmission (92.9%). VDRL test was negative in all 113 patients. Conclusion: The seroprevalence of syphilis in coastal South India using VDRL is very less. Specific tests like Fluorescent Treponemal Antibody Absorption test (FTA-ABS) or Treponema pallidum hemagglutination Assay (TPHA) would be beneficial to detect asymptomatic syphilis in ART centers.
first_indexed 2024-12-11T05:18:07Z
format Article
id doaj.art-b90b4f22a0804d5cba2165023d7d1e70
institution Directory Open Access Journal
issn 2467-9100
2091-0576
language English
last_indexed 2024-12-11T05:18:07Z
publishDate 2015-05-01
publisher Manipal College of Medical Sciences, Pokhara
record_format Article
series Asian Journal of Medical Sciences
spelling doaj.art-b90b4f22a0804d5cba2165023d7d1e702022-12-22T01:19:45ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762015-05-01667779https://doi.org/10.3126/ajms.v6i6.11623Prevalence of Syphilis among People living with HIV (PLHIV) attending a tertiary care hospital in coastal south IndiaDeepak Madi 0Kasturba Medical College, Mangalore Manipal UniversityBackground: Syphilis and HIV are both transmitted sexually so people can be infected with both diseases. Co-infection of syphilis and HIV alters the course of both the diseases. Venereal disease research laboratory (VDRL) test is a non-treponemal test, used commonly in Antiretroviral Therapy Centres (ART) in India to detect syphilis. The aim of our study was to determine the prevalence of syphilis in HIV-infected patients attending a tertiary care hospital using VDRL test. Materials and Methods: Using a cross-sectional study design 113 HIV positive patients were included. VDRL test was used to screen for syphilis. The collected data was analyzed using SPSS version 11.5. Results: Among the 113 patients screened 69(61%) were males and 44(39%) were females. Majority of the patients had acquired the disease through heterosexual transmission (92.9%). VDRL test was negative in all 113 patients. Conclusion: The seroprevalence of syphilis in coastal South India using VDRL is very less. Specific tests like Fluorescent Treponemal Antibody Absorption test (FTA-ABS) or Treponema pallidum hemagglutination Assay (TPHA) would be beneficial to detect asymptomatic syphilis in ART centers.https://www.nepjol.info/index.php/AJMS/article/view/11623syphilishiv / aidsvdrl.
spellingShingle Deepak Madi
Prevalence of Syphilis among People living with HIV (PLHIV) attending a tertiary care hospital in coastal south India
Asian Journal of Medical Sciences
syphilis
hiv / aids
vdrl.
title Prevalence of Syphilis among People living with HIV (PLHIV) attending a tertiary care hospital in coastal south India
title_full Prevalence of Syphilis among People living with HIV (PLHIV) attending a tertiary care hospital in coastal south India
title_fullStr Prevalence of Syphilis among People living with HIV (PLHIV) attending a tertiary care hospital in coastal south India
title_full_unstemmed Prevalence of Syphilis among People living with HIV (PLHIV) attending a tertiary care hospital in coastal south India
title_short Prevalence of Syphilis among People living with HIV (PLHIV) attending a tertiary care hospital in coastal south India
title_sort prevalence of syphilis among people living with hiv plhiv attending a tertiary care hospital in coastal south india
topic syphilis
hiv / aids
vdrl.
url https://www.nepjol.info/index.php/AJMS/article/view/11623
work_keys_str_mv AT deepakmadi prevalenceofsyphilisamongpeoplelivingwithhivplhivattendingatertiarycarehospitalincoastalsouthindia