Virucidal Activity of the Pyridobenzothiazolone Derivative HeE1-17Y against Enveloped RNA Viruses

Virucidal Activity of the Pyridobenzothiazolone Derivative HeE1-17Y against Enveloped RNA Viruses

Pyridobenzothiazolone derivatives are a promising class of broad-spectrum antivirals. However, the mode of action of these compounds remains poorly understood. The HeE1-17Y derivative has already been shown to be a potent compound against a variety of flaviviruses of global relevance. In this work,...

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Bibliographic Details
Main Authors: Rafaela Milan Bonotto, Francesco Bonì, Mario Milani, Antonio Chaves-Sanjuan, Silvia Franze, Francesca Selmin, Tommaso Felicetti, Martino Bolognesi, Soultana Konstantinidou, Monica Poggianella, Chantal L. Márquez, Federica Dattola, Monica Zoppè, Giuseppe Manfroni, Eloise Mastrangelo, Alessandro Marcello
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Viruses
Subjects:
antivirals
enveloped viruses
flavivirus
virucidal effect
reporter replicon particles
Online Access:https://www.mdpi.com/1999-4915/14/6/1157

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