The FcγRIII Engagement Augments PMA-Stimulated Neutrophil Extracellular Traps (NETs) Formation by Granulocytes Partially via Cross-Talk between Syk-ERK-NF-κB and PKC-ROS Signaling Pathways

The FcγRIII Engagement Augments PMA-Stimulated Neutrophil Extracellular Traps (NETs) Formation by Granulocytes Partially via Cross-Talk between Syk-ERK-NF-κB and PKC-ROS Signaling Pathways

Polymorphonuclear neutrophils (PMNs) are the most abundant white blood cell in the circulation capable of neutrophil extracellular traps (NETs) formation after stimulation. Both NADPH oxidase-dependent and -independent pathways are involved in NET formation. The IgG is the most abundant immunoglobul...

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Bibliographic Details
Main Authors:	Cheng-Hsun Lu, Ko-Jen Li, Cheng-Han Wu, Chieh-Yu Shen, Yu-Min Kuo, Song-Chou Hsieh, Chia-Li Yu
Format:	Article
Language:	English
Published:	MDPI AG 2021-09-01
Series:	Biomedicines
Subjects:	polymorphonuclear neutrophil neutrophil extracellular traps differentiated HL-60 cells IgG subclass FcγRIII engagement reactive oxygen species
Online Access:	https://www.mdpi.com/2227-9059/9/9/1127

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