DNA repair factor KAT5 prevents ischemic acute kidney injury through glomerular filtration regulation

DNA repair factor KAT5 prevents ischemic acute kidney injury through glomerular filtration regulation

Summary: The “preconditioning effect” in AKI is a phenomenon in which an episode of ischemia-reperfusion results in tolerance to subsequent ischemia-reperfusion injury. However, its relationship between DNA damage repair has not been elucidated. Here, we show the role of KAT5 in the preconditioning...

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Bibliographic Details
Main Authors: Akihito Hishikawa, Kaori Hayashi, Akiko Kubo, Kazutoshi Miyashita, Akinori Hashiguchi, Kenichiro Kinouchi, Norifumi Yoshimoto, Ran Nakamichi, Riki Akashio, Erina Sugita, Tatsuhiko Azegami, Toshiaki Monkawa, Makoto Suematsu, Hiroshi Itoh
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:iScience
Subjects:
Pathophysiology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221014073

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