Bone metastases in hepatoblastoma, an unusual presentation. Case report and review of the literature
Primary liver tumors are rare in childhood. Hepatoblastoma is the most prevalent and has a variable clinical presentation. The initial approach requires clinical suspicion, histopathological confirmation, and measurement of AFP levels, in addition to PRETEXT staging by abdominal computed tomography....
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-11-01
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| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043322006860 |
| _version_ | 1811208699171045376 |
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| author | Viviana Barragan, MD Maria Camila Escudero, MD Ivette C. Jimenez, MD Catalina Correa, MD Juan Pablo Luengas, MD |
| author_facet | Viviana Barragan, MD Maria Camila Escudero, MD Ivette C. Jimenez, MD Catalina Correa, MD Juan Pablo Luengas, MD |
| author_sort | Viviana Barragan, MD |
| collection | DOAJ |
| description | Primary liver tumors are rare in childhood. Hepatoblastoma is the most prevalent and has a variable clinical presentation. The initial approach requires clinical suspicion, histopathological confirmation, and measurement of AFP levels, in addition to PRETEXT staging by abdominal computed tomography. PET-CT is useful in metastatic disease for diagnosis and evaluation of therapeutic response. Pulmonary metastases at the time of diagnosis are frequent, while bone metastases are rare. We present the case of an infant with a history of metastatic hepatoblastoma, multiple relapses, and poor response to multimodal management. The patient had bone metastases demonstrated by PET-CT imaging. |
| first_indexed | 2024-04-12T04:27:10Z |
| format | Article |
| id | doaj.art-b91625c912654255a9f6b2793595dcff |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-04-12T04:27:10Z |
| publishDate | 2022-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-b91625c912654255a9f6b2793595dcff2022-12-22T03:48:04ZengElsevierRadiology Case Reports1930-04332022-11-01171142724275Bone metastases in hepatoblastoma, an unusual presentation. Case report and review of the literatureViviana Barragan, MD0Maria Camila Escudero, MD1Ivette C. Jimenez, MD2Catalina Correa, MD3Juan Pablo Luengas, MD4Universidad Militar Nueva Granada, Hospital Militar Central, Bogotá, DC, ColombiaUniversidad de La Sabana, Bogotá, DC, ColombiaUniversidad El Bosque, Bogotá, DC, ColombiaHospital Militar Central, Bogotá D.C, ColombiaInstituto Nacional de Cancerología, Bogotá́, DC, ColombiaPrimary liver tumors are rare in childhood. Hepatoblastoma is the most prevalent and has a variable clinical presentation. The initial approach requires clinical suspicion, histopathological confirmation, and measurement of AFP levels, in addition to PRETEXT staging by abdominal computed tomography. PET-CT is useful in metastatic disease for diagnosis and evaluation of therapeutic response. Pulmonary metastases at the time of diagnosis are frequent, while bone metastases are rare. We present the case of an infant with a history of metastatic hepatoblastoma, multiple relapses, and poor response to multimodal management. The patient had bone metastases demonstrated by PET-CT imaging.http://www.sciencedirect.com/science/article/pii/S1930043322006860HepatoblastomaNeoplasm stagingAlpha-fetoproteinNeoplasm metastasisBoneTherapeutics |
| spellingShingle | Viviana Barragan, MD Maria Camila Escudero, MD Ivette C. Jimenez, MD Catalina Correa, MD Juan Pablo Luengas, MD Bone metastases in hepatoblastoma, an unusual presentation. Case report and review of the literature Radiology Case Reports Hepatoblastoma Neoplasm staging Alpha-fetoprotein Neoplasm metastasis Bone Therapeutics |
| title | Bone metastases in hepatoblastoma, an unusual presentation. Case report and review of the literature |
| title_full | Bone metastases in hepatoblastoma, an unusual presentation. Case report and review of the literature |
| title_fullStr | Bone metastases in hepatoblastoma, an unusual presentation. Case report and review of the literature |
| title_full_unstemmed | Bone metastases in hepatoblastoma, an unusual presentation. Case report and review of the literature |
| title_short | Bone metastases in hepatoblastoma, an unusual presentation. Case report and review of the literature |
| title_sort | bone metastases in hepatoblastoma an unusual presentation case report and review of the literature |
| topic | Hepatoblastoma Neoplasm staging Alpha-fetoprotein Neoplasm metastasis Bone Therapeutics |
| url | http://www.sciencedirect.com/science/article/pii/S1930043322006860 |
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