Proteasomes of Autophagy-Deficient Cells Exhibit Alterations in Regulatory Proteins and a Marked Reduction in Activity

Proteasomes of Autophagy-Deficient Cells Exhibit Alterations in Regulatory Proteins and a Marked Reduction in Activity

Autophagy and the ubiquitin proteasome system are the two major processes for the clearance and recycling of proteins and organelles in eukaryotic cells. Evidence is accumulating that there is extensive crosstalk between the two pathways, but the underlying mechanisms are still unclear. We previousl...

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Bibliographic Details
Main Authors: Qiuhong Xiong, Rong Feng, Sarah Fischer, Malte Karow, Maria Stumpf, Susanne Meßling, Leonie Nitz, Stefan Müller, Christoph S. Clemen, Ning Song, Ping Li, Changxin Wu, Ludwig Eichinger
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cells
Subjects:
autophagy
ubiquitin proteasome system (UPS)
<i>Dictyostelium</i>
ATG9
ATG16
Online Access:https://www.mdpi.com/2073-4409/12/11/1514

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