Striatal reactivity to reward under threat-of-shock and working memory load in adults at increased familial risk for major depression: A preliminary study

Striatal reactivity to reward under threat-of-shock and working memory load in adults at increased familial risk for major depression: A preliminary study

Introduction: Anhedonia, a core symptom of Major Depressive Disorder (MDD), manifests as a lack or loss of motivation as reflected by decreased reward responsiveness, at both behavioral and neural (i.e., striatum) levels. Exposure to stressful life events is another important risk factor for MDD. Ho...

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Bibliographic Details
Main Authors: Claudie Gaillard, Matthias Guillod, Monique Ernst, Andrea Federspiel, Dominik Schoebi, Romina Evelyn Recabarren, Xinyi Ouyang, Christoph Mueller-Pfeiffer, Antje Horsch, Philipp Homan, Roland Wiest, Gregor Hasler, Chantal Martin-Soelch
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:NeuroImage: Clinical
Subjects:
Vulnerability
Major depressive disorder
Reward
Stress
Striatum
fMRI
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158220300309

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