Regulatory Effects of Apatinib in Combination with Piperine on MDM-2 Gene Expression, Glutathione Peroxidase Activity and Nitric Oxide level as Mechanisms of Cytotoxicity in Colorectal Cancer Cells

Regulatory Effects of Apatinib in Combination with Piperine on MDM-2 Gene Expression, Glutathione Peroxidase Activity and Nitric Oxide level as Mechanisms of Cytotoxicity in Colorectal Cancer Cells

Purpose: Apatinib has been utilized in colon cancer therapies but its efficiency and molecularmechanism are not fully understood. Chemotherapy in combination with non-toxic compoundscan be an effective treatment strategy for cancer. Consequently, this study was carried out toevaluate the effects of...

Full description

Bibliographic Details
Main Authors: Mahshid Mohammadian, Zakieh Rostamzadeh Khameneh, Soraya Emamgholizadeh Minaei, Meysam Ebrahimifar, Kosar Esgandari
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2022-03-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
colorectal cancer
apoptosis
hct-116 cells
apatinib
piperine
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-12-404.pdf

Similar Items

Similar Items