Occurrence of mecA and blaZ genes in methicillin-resistant Staphylococcus aureus associated with vaginitis among pregnant women in Ado-Ekiti, Nigeria

Methicillin-resistant Staphylococcus aureus (MRSA) is an increasingly prevalent pathogen. We studied the prevalence of MRSA and its association with vaginitis during pregnancy. Bacteriological investigations of high vaginal swabs of 350 healthy pregnant women attending antenatal clinics were carried...

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Main Authors: P.A. Okiki, E.S. Eromosele, P. Ade-Ojo, O.A. Sobajo, O.O. Idris, R.D. Agbana
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:New Microbes and New Infections
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2052297520301244
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author P.A. Okiki
E.S. Eromosele
P. Ade-Ojo
O.A. Sobajo
O.O. Idris
R.D. Agbana
author_facet P.A. Okiki
E.S. Eromosele
P. Ade-Ojo
O.A. Sobajo
O.O. Idris
R.D. Agbana
author_sort P.A. Okiki
collection DOAJ
description Methicillin-resistant Staphylococcus aureus (MRSA) is an increasingly prevalent pathogen. We studied the prevalence of MRSA and its association with vaginitis during pregnancy. Bacteriological investigations of high vaginal swabs of 350 healthy pregnant women attending antenatal clinics were carried out. Staphylococci were isolated from high vaginal swabs of 135 of the women. The staphylococcal isolates were resistant to multiple antibiotics. The PCR amplification of DNA of 20 selected isolates yielded six possessing the mecA gene and 13 the blaZ gene. MRSA possessing both the mecA and blaZ genes were isolated from subjects who reported vaginal discharge and itching.
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spelling doaj.art-b9229ef8a8e342b68cbeaf06cee953e62022-12-21T19:58:01ZengElsevierNew Microbes and New Infections2052-29752020-11-0138100772Occurrence of mecA and blaZ genes in methicillin-resistant Staphylococcus aureus associated with vaginitis among pregnant women in Ado-Ekiti, NigeriaP.A. Okiki0E.S. Eromosele1P. Ade-Ojo2O.A. Sobajo3O.O. Idris4R.D. Agbana5Department of Biological Sciences, College of Sciences, Nigeria; Corresponding author: P. A. Okiki, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria.Department of Biological Sciences, College of Sciences, NigeriaDepartment of Obstetrics and Gynaecology, Ekiti State University Teaching Hospital, Ado-Ekiti, NigeriaDepartment of Biological Sciences, College of Sciences, NigeriaDepartment of Biological Sciences, College of Sciences, NigeriaDepartment of Community Medicine, College of Medicine and Health Sciences, Afe Babalola University, NigeriaMethicillin-resistant Staphylococcus aureus (MRSA) is an increasingly prevalent pathogen. We studied the prevalence of MRSA and its association with vaginitis during pregnancy. Bacteriological investigations of high vaginal swabs of 350 healthy pregnant women attending antenatal clinics were carried out. Staphylococci were isolated from high vaginal swabs of 135 of the women. The staphylococcal isolates were resistant to multiple antibiotics. The PCR amplification of DNA of 20 selected isolates yielded six possessing the mecA gene and 13 the blaZ gene. MRSA possessing both the mecA and blaZ genes were isolated from subjects who reported vaginal discharge and itching.http://www.sciencedirect.com/science/article/pii/S2052297520301244Ado-EkitimecA and blaZ genesMethicillin-resistant Staphylococcus aureuspregnancyvaginitis
spellingShingle P.A. Okiki
E.S. Eromosele
P. Ade-Ojo
O.A. Sobajo
O.O. Idris
R.D. Agbana
Occurrence of mecA and blaZ genes in methicillin-resistant Staphylococcus aureus associated with vaginitis among pregnant women in Ado-Ekiti, Nigeria
New Microbes and New Infections
Ado-Ekiti
mecA and blaZ genes
Methicillin-resistant Staphylococcus aureus
pregnancy
vaginitis
title Occurrence of mecA and blaZ genes in methicillin-resistant Staphylococcus aureus associated with vaginitis among pregnant women in Ado-Ekiti, Nigeria
title_full Occurrence of mecA and blaZ genes in methicillin-resistant Staphylococcus aureus associated with vaginitis among pregnant women in Ado-Ekiti, Nigeria
title_fullStr Occurrence of mecA and blaZ genes in methicillin-resistant Staphylococcus aureus associated with vaginitis among pregnant women in Ado-Ekiti, Nigeria
title_full_unstemmed Occurrence of mecA and blaZ genes in methicillin-resistant Staphylococcus aureus associated with vaginitis among pregnant women in Ado-Ekiti, Nigeria
title_short Occurrence of mecA and blaZ genes in methicillin-resistant Staphylococcus aureus associated with vaginitis among pregnant women in Ado-Ekiti, Nigeria
title_sort occurrence of meca and blaz genes in methicillin resistant staphylococcus aureus associated with vaginitis among pregnant women in ado ekiti nigeria
topic Ado-Ekiti
mecA and blaZ genes
Methicillin-resistant Staphylococcus aureus
pregnancy
vaginitis
url http://www.sciencedirect.com/science/article/pii/S2052297520301244
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