Posttraumatic midazolam administration does not influence brain damage after experimental traumatic brain injury

Posttraumatic midazolam administration does not influence brain damage after experimental traumatic brain injury

Abstract Background The benzodiazepine midazolam is a γ-aminobutyric acid (GABA)-A receptor agonist frequently used for sedation or stress control in patients suffering from traumatic brain injury (TBI). However, experimental studies on benzodiazepines have reported divergent results, raising concer...

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Bibliographic Details
Main Authors: Anne Sebastiani, Simone Bender, Michael K. E. Schäfer, Serge C. Thal
Format: Article
Language:English
Published: BMC 2022-03-01
Series:BMC Anesthesiology
Subjects:
Midazolam
Flumazenil
Benzodiazepines
γ-aminobutyric acid-A receptor
Neurotoxicity
Traumatic brain injury
Online Access:https://doi.org/10.1186/s12871-022-01592-x

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