Prognostic impact of radiotherapy-induced-lymphopenia in patients treated with breast-conservative surgery

Prognostic impact of radiotherapy-induced-lymphopenia in patients treated with breast-conservative surgery

Abstract We investigated a prognostic impact of radiotherapy-induced lymphopenia (RIL) in breast cancer patients treated with breast-conservative surgery (BCS). We included 531 breast cancer patients who were treated with BCS and adjuvant radiotherapy. None of these received (neo)adjuvant chemothera...

Full description

Bibliographic Details
Main Authors:	Chang Ik Yoon, Jawon Hwang, Dooreh Kim, Jung Hwan Ji, Janghee Lee, Soong June Bae, Joon Jeong, Jee-Suk Chang, Yeona Cho, Hye Sun Lee, Jee Ye Kim, Sung Gwe Ahn
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-09-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-023-41301-3

Similar Items

Radiation dose-event relationship after intraoperative radiotherapy as a boost in patients with breast cancer
by: Yeona Cho, et al.
Published: (2023-05-01)

The Impact of Post-Mastectomy Radiotherapy on Survival Outcomes in Breast Cancer Patients Who Underwent Neoadjuvant Chemotherapy
by: Janghee Lee, et al.
Published: (2021-12-01)

Application of the 21-Gene Recurrence Score in Patients with Early HR-Positive/HER2-Negative Breast Cancer: Chemotherapy and Survival Rate According to Clinical Risk
by: Soong June Bae, et al.
Published: (2021-08-01)

Radiotherapy-Induced High Neutrophil-to-Lymphocyte Ratio is a Negative Prognostic Factor in Patients with Breast Cancer
by: Chang Ik Yoon, et al.
Published: (2020-07-01)

Comparison of complications according to incision types in nipple-sparing mastectomy and immediate reconstruction
by: Soeun Park, et al.
Published: (2020-10-01)

Primary endocrine resistance of ER+ breast cancer with ESR1 mutations interrogated by droplet digital PCR
by: Sung Gwe Ahn, et al.
Published: (2022-05-01)

Author Correction: Primary endocrine resistance of ER+ breast cancer with ESR1 mutations interrogated by droplet digital PCR
by: Sung Gwe Ahn, et al.
Published: (2022-05-01)

Relationship of the standard uptake value of 18F-FDG-PET-CT with tumor-infiltrating lymphocytes in breast tumors measuring ≥ 1 cm
by: Soeun Park, et al.
Published: (2021-06-01)

Residual Tumor Patterns of Breast Cancer on MRI after Neo-Adjuvant Chemotherapy: Impact on Clinicopathologic Factors and Prognosis
by: Yoon Jin Cha, et al.
Published: (2022-09-01)

YAP1 Expression in HR+HER2− Breast Cancer: 21-Gene Recurrence Score Analysis and Public Dataset Validation
by: Inho Park, et al.
Published: (2023-10-01)

Author Correction: Validation of Clinical Treatment Score post-5 years (CTS5) risk stratification in premenopausal breast cancer patients and Ki-67 labelling index
by: Janghee Lee, et al.
Published: (2021-03-01)

Metastasis Risk Assessment Using BAG2 Expression by Cancer-Associated Fibroblast and Tumor Cells in Patients with Breast Cancer
by: Chang-Ik Yoon, et al.
Published: (2021-09-01)

18F-FDG uptake of visceral adipose tissue on preoperative PET/CT as a predictive marker for breast cancer recurrence
by: Hyun Jeong Kim, et al.
Published: (2022-12-01)

SP142 PD-L1 Assays in Multiple Samples from the Same Patients with Early or Advanced Triple-Negative Breast Cancer
by: Seung Ho Baek, et al.
Published: (2022-06-01)

BRCA1 mutation promotes sprouting angiogenesis in inflammatory cancer-associated fibroblast of triple-negative breast cancer
by: Chae Min Lee, et al.
Published: (2024-01-01)

The association between the expression of nuclear Yes-associated protein 1 (YAP1) and p53 protein expression profile in breast cancer patients.
by: Yoon Jin Cha, et al.
Published: (2021-01-01)

Association between TP53 mutation and high 21-gene recurrence score in estrogen receptor-positive/HER2-negative breast cancer
by: Jung Hwan Ji, et al.
Published: (2022-02-01)

Association between Skeletal Muscle Loss and the Response to Neoadjuvant Chemotherapy for Breast Cancer
by: Byung Min Lee, et al.
Published: (2021-04-01)

Associations between absolute neutrophil count and lymphocyte-predominant breast cancer
by: Chang Ik Yoon, et al.
Published: (2020-04-01)

Predictive Markers of Treatment Response to Neoadjuvant Systemic Therapy with Dual HER2-Blockade
by: Soong June Bae, et al.
Published: (2024-02-01)

Real-World Clinical Outcomes of Biosimilar Trastuzumab (CT-P6) in HER2-Positive Early-Stage and Metastatic Breast Cancer
by: Soong June Bae, et al.
Published: (2021-06-01)

Anaemia and pathologic complete response rate according to carboplatin dose in HER2+ breast cancer treated with neoadjuvant TCHP
by: Jung Hwan Ji, et al.
Published: (2023-01-01)

Evaluation of optimal treatment planning for radiotherapy of synchronous bilateral breast cancer including regional lymph node irradiation
by: Yeona Cho, et al.
Published: (2019-04-01)

Tumor-Infiltrating Lymphocyte Level Consistently Correlates with Lower Stiffness Measured by Shear-Wave Elastography: Subtype-Specific Analysis of Its Implication in Breast Cancer
by: Na Lae Eun, et al.
Published: (2024-03-01)

Neural network based ensemble model to predict radiation induced lymphopenia after concurrent chemo-radiotherapy for non-small cell lung cancer from two institutions
by: Yejin Kim, et al.
Published: (2023-05-01)

Does Radiotherapy for the Primary Tumor Benefit Prostate Cancer Patients with Distant Metastasis at Initial Diagnosis?
by: Yeona Cho, et al.
Published: (2016-01-01)

Correlation of Yes-Associated Protein 1 with Stroma Type and Tumor Stiffness in Hormone-Receptor Positive Breast Cancer
by: Yangkyu Lee, et al.
Published: (2022-10-01)

Chondroradionecrosis of the trachea after definitive radiotherapy for cervical esophageal cancer: A case report
by: Jina Kim, et al.
Published: (2021-09-01)

Elasticity Values as a Predictive Modality for Response to Neoadjuvant Chemotherapy in Breast Cancer
by: Min Ji Kim, et al.
Published: (2024-01-01)

Normal tissue complication probability models of hypothyroidism after radiotherapy for breast cancer
by: Ye-In Park, et al.
Published: (2024-03-01)

Chemosensitivity to doxorubicin of ER-positive/HER2-negative breast cancers with high 21-gene recurrence score: A study based on in vitro chemoresponse assay.
by: Sung Gwe Ahn, et al.
Published: (2017-01-01)

Hypofractionated Radiotherapy Dose Scheme and Application of New Techniques Are Associated to a Lower Incidence of Radiation Pneumonitis in Breast Cancer Patients
by: Byung Min Lee, et al.
Published: (2020-02-01)

Lymphopenia, Lymphopenia-Induced Proliferation, and Autoimmunity
by: Ting-Ting Sheu, et al.
Published: (2021-04-01)

Skeletal Muscle Depletion Predicts the Prognosis of Patients With Hepatocellular Carcinoma Treated With Radiotherapy
by: Joongyo Lee, et al.
Published: (2019-10-01)

Comprehensive clinical evaluation of deep learning-based auto-segmentation for radiotherapy in patients with cervical cancer
by: Seung Yeun Chung, et al.
Published: (2023-04-01)

Lymphopenia is an important prognostic factor in peripheral T-cell lymphoma (NOS) treated with anthracycline-containing chemotherapy
by: Jeong Seong Hyun, et al.
Published: (2011-08-01)

Optimal treatment strategy for hormone receptor-positive human epidermal growth factor receptor 2-negative breast cancer patients with 1–2 suspicious axillary lymph node metastases on breast magnetic resonance imaging: upfront surgery vs. neoadjuvant chemotherapy
by: Seung Eun Lee, et al.
Published: (2023-05-01)

Prognostic implication of simultaneous anemia and lymphopenia during concurrent chemoradiotherapy in cervical squamous cell carcinoma
by: Oyeon Cho, et al.
Published: (2017-10-01)

Association between tamoxifen and incidence of osteoporosis in Korean patients with ductal carcinoma in situ
by: Dooreh Kim, et al.
Published: (2024-01-01)

Risk of Secondary Cancer after Adjuvant Tamoxifen Treatment for Ductal Carcinoma In Situ: A Nationwide Cohort Study in South Korea
by: Dooreh Kim, et al.
Published: (2023-02-01)