Association between selenium intake and cognitive function among older adults in the US: National Health and Nutrition Examination Surveys 2011–2014
Cognitive decline occurs commonly as people age. Despite the complexity of cellular mechanisms, oxidative stress is a critical contributor to age-associated cognitive impairment. Selenium plays an important role in antioxidant defense systems. The purpose of the present study was to assess the corre...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2023-01-01
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| Series: | Journal of Nutritional Science |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2048679023000435/type/journal_article |
| _version_ | 1797829780577452032 |
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| author | Khondoker Adeba Ferdous Linda L Knol Han-A Park |
| author_facet | Khondoker Adeba Ferdous Linda L Knol Han-A Park |
| author_sort | Khondoker Adeba Ferdous |
| collection | DOAJ |
| description | Cognitive decline occurs commonly as people age. Despite the complexity of cellular mechanisms, oxidative stress is a critical contributor to age-associated cognitive impairment. Selenium plays an important role in antioxidant defense systems. The purpose of the present study was to assess the correlation between selenium intake and cognitive function among older adults. The participants were individuals ≥65 years old (n=1681) who participated in the 2011–2014 National Health and Nutrition Examination Survey (NHANES), a country-wide cross-sectional survey. Dietary selenium intake and adequacy were evaluated with 2 d of 24-h recalls and the estimated average requirement (EAR) cut-point method, respectively. Cognitive function was assessed with the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) score, which was significantly higher when selenium intake was adequate. After adjusting for energy intake, the association was no longer significant. Inadequate intake of selenium is rare in the US and dependent on caloric intake in older adults. |
| first_indexed | 2024-04-09T13:26:43Z |
| format | Article |
| id | doaj.art-b9263cb413f144f7b6acb67120900960 |
| institution | Directory Open Access Journal |
| issn | 2048-6790 |
| language | English |
| last_indexed | 2024-04-09T13:26:43Z |
| publishDate | 2023-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Journal of Nutritional Science |
| spelling | doaj.art-b9263cb413f144f7b6acb671209009602023-05-10T09:23:12ZengCambridge University PressJournal of Nutritional Science2048-67902023-01-011210.1017/jns.2023.43Association between selenium intake and cognitive function among older adults in the US: National Health and Nutrition Examination Surveys 2011–2014Khondoker Adeba Ferdous0Linda L Knol1Han-A Park2Department of Human Nutrition and Hospitality Management, College of Human Environmental Sciences, The University of Alabama, PO Box 870311, Tuscaloosa, AL 35487, USADepartment of Human Nutrition and Hospitality Management, College of Human Environmental Sciences, The University of Alabama, PO Box 870311, Tuscaloosa, AL 35487, USADepartment of Human Nutrition and Hospitality Management, College of Human Environmental Sciences, The University of Alabama, PO Box 870311, Tuscaloosa, AL 35487, USACognitive decline occurs commonly as people age. Despite the complexity of cellular mechanisms, oxidative stress is a critical contributor to age-associated cognitive impairment. Selenium plays an important role in antioxidant defense systems. The purpose of the present study was to assess the correlation between selenium intake and cognitive function among older adults. The participants were individuals ≥65 years old (n=1681) who participated in the 2011–2014 National Health and Nutrition Examination Survey (NHANES), a country-wide cross-sectional survey. Dietary selenium intake and adequacy were evaluated with 2 d of 24-h recalls and the estimated average requirement (EAR) cut-point method, respectively. Cognitive function was assessed with the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) score, which was significantly higher when selenium intake was adequate. After adjusting for energy intake, the association was no longer significant. Inadequate intake of selenium is rare in the US and dependent on caloric intake in older adults.https://www.cambridge.org/core/product/identifier/S2048679023000435/type/journal_articleAgeCERADCognitionNHANESSelenium |
| spellingShingle | Khondoker Adeba Ferdous Linda L Knol Han-A Park Association between selenium intake and cognitive function among older adults in the US: National Health and Nutrition Examination Surveys 2011–2014 Journal of Nutritional Science Age CERAD Cognition NHANES Selenium |
| title | Association between selenium intake and cognitive function among older adults in the US: National Health and Nutrition Examination Surveys 2011–2014 |
| title_full | Association between selenium intake and cognitive function among older adults in the US: National Health and Nutrition Examination Surveys 2011–2014 |
| title_fullStr | Association between selenium intake and cognitive function among older adults in the US: National Health and Nutrition Examination Surveys 2011–2014 |
| title_full_unstemmed | Association between selenium intake and cognitive function among older adults in the US: National Health and Nutrition Examination Surveys 2011–2014 |
| title_short | Association between selenium intake and cognitive function among older adults in the US: National Health and Nutrition Examination Surveys 2011–2014 |
| title_sort | association between selenium intake and cognitive function among older adults in the us national health and nutrition examination surveys 2011 2014 |
| topic | Age CERAD Cognition NHANES Selenium |
| url | https://www.cambridge.org/core/product/identifier/S2048679023000435/type/journal_article |
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