Transforming growth factor beta receptor 2 single-nucleotide polymorphism association with oral cancer and In silico identification of small drug-like molecules as inhibitors to transforming growth factor Beta-2 receptor

Transforming growth factor beta receptor 2 single-nucleotide polymorphism association with oral cancer and In silico identification of small drug-like molecules as inhibitors to transforming growth factor Beta-2 receptor

Objective: Oral cancer, in India, constitutes 26% of global oral cancer burden. The major risk factors include tobacco, areca nut, alcohol, and human papillomavirus 16/18; however, only 5%–10% of the high-risk individuals develop oral cancer, indicating the role of genomic variants in susceptibility...

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Bibliographic Details
Main Authors: Shaleen Multani, Hetal Damani Shah, Dhananjaya Saranath
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Biomedical Research Journal
Subjects:
in silico analysis
oral cancer
risk
single-nucleotide polymorphisms
tgfbr2
virtual screening
Online Access:http://www.brjnmims.org/article.asp?issn=2349-3666;year=2019;volume=6;issue=1;spage=25;epage=33;aulast=Multani

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