An Indole-Based Fluorescent Chemosensor for Detecting Zn<sup>2+</sup> in Aqueous Media and Zebrafish
An indole-based fluorescent chemosensor <b>IH-Sal</b> was synthesized to detect Zn<sup>2+</sup>. <b>IH-Sal</b> displayed a marked fluorescence increment with Zn<sup>2+</sup>. The detection limit (0.41 μM) of <b>IH-Sal</b> for Zn<sup>2...
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MDPI AG
2021-08-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/21/16/5591 |
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| author | Donghwan Choe Haeri So Soyoung Park Hangyul Lee Ju Byeong Chae Jiwon Kim Ki-Tae Kim Cheal Kim |
| author_facet | Donghwan Choe Haeri So Soyoung Park Hangyul Lee Ju Byeong Chae Jiwon Kim Ki-Tae Kim Cheal Kim |
| author_sort | Donghwan Choe |
| collection | DOAJ |
| description | An indole-based fluorescent chemosensor <b>IH-Sal</b> was synthesized to detect Zn<sup>2+</sup>. <b>IH-Sal</b> displayed a marked fluorescence increment with Zn<sup>2+</sup>. The detection limit (0.41 μM) of <b>IH-Sal</b> for Zn<sup>2+</sup> was greatly below that suggested by the World Health Organization. <b>IH-Sal</b> can quantify Zn<sup>2+</sup> in real water samples. More significantly, <b>IH-Sal</b> could determine and depict the presence of Zn<sup>2+</sup> in zebrafish. The detecting mechanism of <b>IH-Sal</b> toward Zn<sup>2+</sup> was illustrated by fluorescence and UV–visible spectroscopy, DFT calculations, <sup>1</sup>H NMR titration and ESI mass. |
| first_indexed | 2024-03-10T08:23:43Z |
| format | Article |
| id | doaj.art-b929825b330a4828875df97261b497d7 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-10T08:23:43Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-b929825b330a4828875df97261b497d72023-11-22T09:42:33ZengMDPI AGSensors1424-82202021-08-012116559110.3390/s21165591An Indole-Based Fluorescent Chemosensor for Detecting Zn<sup>2+</sup> in Aqueous Media and ZebrafishDonghwan Choe0Haeri So1Soyoung Park2Hangyul Lee3Ju Byeong Chae4Jiwon Kim5Ki-Tae Kim6Cheal Kim7Department of Fine Chem and Renewable Energy Convergence, Seoul National University of Science and Technology (SNUT), Seoul 139-743, KoreaDepartment of Fine Chem and Renewable Energy Convergence, Seoul National University of Science and Technology (SNUT), Seoul 139-743, KoreaDepartment of Fine Chem and Renewable Energy Convergence, Seoul National University of Science and Technology (SNUT), Seoul 139-743, KoreaDepartment of Fine Chem and Renewable Energy Convergence, Seoul National University of Science and Technology (SNUT), Seoul 139-743, KoreaDepartment of Fine Chem and Renewable Energy Convergence, Seoul National University of Science and Technology (SNUT), Seoul 139-743, KoreaDepartment of Environmental Engineering, Seoul National University of Science and Technology (SNUT), Seoul 139-743, KoreaDepartment of Environmental Engineering, Seoul National University of Science and Technology (SNUT), Seoul 139-743, KoreaDepartment of Fine Chem and Renewable Energy Convergence, Seoul National University of Science and Technology (SNUT), Seoul 139-743, KoreaAn indole-based fluorescent chemosensor <b>IH-Sal</b> was synthesized to detect Zn<sup>2+</sup>. <b>IH-Sal</b> displayed a marked fluorescence increment with Zn<sup>2+</sup>. The detection limit (0.41 μM) of <b>IH-Sal</b> for Zn<sup>2+</sup> was greatly below that suggested by the World Health Organization. <b>IH-Sal</b> can quantify Zn<sup>2+</sup> in real water samples. More significantly, <b>IH-Sal</b> could determine and depict the presence of Zn<sup>2+</sup> in zebrafish. The detecting mechanism of <b>IH-Sal</b> toward Zn<sup>2+</sup> was illustrated by fluorescence and UV–visible spectroscopy, DFT calculations, <sup>1</sup>H NMR titration and ESI mass.https://www.mdpi.com/1424-8220/21/16/5591zinc ionindolefluorescent chemosensorcalculationsbio-imaging |
| spellingShingle | Donghwan Choe Haeri So Soyoung Park Hangyul Lee Ju Byeong Chae Jiwon Kim Ki-Tae Kim Cheal Kim An Indole-Based Fluorescent Chemosensor for Detecting Zn<sup>2+</sup> in Aqueous Media and Zebrafish Sensors zinc ion indole fluorescent chemosensor calculations bio-imaging |
| title | An Indole-Based Fluorescent Chemosensor for Detecting Zn<sup>2+</sup> in Aqueous Media and Zebrafish |
| title_full | An Indole-Based Fluorescent Chemosensor for Detecting Zn<sup>2+</sup> in Aqueous Media and Zebrafish |
| title_fullStr | An Indole-Based Fluorescent Chemosensor for Detecting Zn<sup>2+</sup> in Aqueous Media and Zebrafish |
| title_full_unstemmed | An Indole-Based Fluorescent Chemosensor for Detecting Zn<sup>2+</sup> in Aqueous Media and Zebrafish |
| title_short | An Indole-Based Fluorescent Chemosensor for Detecting Zn<sup>2+</sup> in Aqueous Media and Zebrafish |
| title_sort | indole based fluorescent chemosensor for detecting zn sup 2 sup in aqueous media and zebrafish |
| topic | zinc ion indole fluorescent chemosensor calculations bio-imaging |
| url | https://www.mdpi.com/1424-8220/21/16/5591 |
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