Validation of the state version questionnaire on autonomic regulation (state-aR) for cancer patients
<p>Abstract</p> <p>Objectives</p> <p>Current quality of life inventories used in oncology mainly measure the effects of chemo- or radiotherapy alongside functional and role scales. A new approach is to measure the autonomic state of regulation with the trait-inventory o...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-10-01
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| Series: | European Journal of Medical Research |
| Subjects: | |
| Online Access: | http://www.eurjmedres.com/content/16/10/457 |
| _version_ | 1811252460853919744 |
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| author | Kröz M Schad F Reif M von Laue HB Feder G Zerm R Willich SN Girke M Brinkhaus B |
| author_facet | Kröz M Schad F Reif M von Laue HB Feder G Zerm R Willich SN Girke M Brinkhaus B |
| author_sort | Kröz M |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Objectives</p> <p>Current quality of life inventories used in oncology mainly measure the effects of chemo- or radiotherapy alongside functional and role scales. A new approach is to measure the autonomic state of regulation with the trait-inventory of autonomic regulation (Trait-aR). Loss of Trait-aR has been shown in different medical conditions such as breast cancer (BC) but not in colorectal cancer patients (CRC). In this paper we report the validation of a new state autonomic regulation scale (State-aR) of the last week.</p> <p>Methods</p> <p>Study 1 included 114 participants: (41 women/16 men with cancer and 57 age- and gender-matched healthy people) to conduct a reliability-, factor- and validity-analysis. Concurrent and convergent validity was evaluated with Trait-aR, Fatigue-Numeri-cal-Scale, Hospital Anxiety and Depression Scale (HADS-D) and the self-regulation scale, 65 participants were retested. Study 2 completed 42 participants: 17 with BC and 25 with CRC receiving chemotherapy. The State-aR was administered prior, during and after chemotherapy for measuring responsiveness.</p> <p>Results</p> <p>The factor analysis loaded to four subscales of State-aR (rest-activity, orthostatic-circulatory, thermosweating and digestive regulation) with a: Cronbach-α r<sub>α </sub>= 0.77-0.83 and a test-retest-reliability r<sub>rt </sub>= 0.60-0.80. The sum- and sub scales correlated with their concurrent subscales in the Trait-aR (0.48-0.74) and with the sum-scale moderately with all convergent criteria (r = 0.41 --0.44; p < 0.001). During chemotherapy the State-aR-sum and rest-activity-scale decreased significantly compared to the change in the Trait-aR (p < 0.05).</p> <p>Conclusions</p> <p>These findings support that the state autonomic regulation scale has satisfactory to good reliability, good validity and acceptable responsiveness in the context of chemotherapy treatment.</p> |
| first_indexed | 2024-04-12T16:34:59Z |
| format | Article |
| id | doaj.art-b92ccffd98f8420fbc94a7e804550765 |
| institution | Directory Open Access Journal |
| issn | 2047-783X |
| language | English |
| last_indexed | 2024-04-12T16:34:59Z |
| publishDate | 2011-10-01 |
| publisher | BMC |
| record_format | Article |
| series | European Journal of Medical Research |
| spelling | doaj.art-b92ccffd98f8420fbc94a7e8045507652022-12-22T03:25:01ZengBMCEuropean Journal of Medical Research2047-783X2011-10-01161045710.1186/2047-783X-16-10-457Validation of the state version questionnaire on autonomic regulation (state-aR) for cancer patientsKröz MSchad FReif Mvon Laue HBFeder GZerm RWillich SNGirke MBrinkhaus B<p>Abstract</p> <p>Objectives</p> <p>Current quality of life inventories used in oncology mainly measure the effects of chemo- or radiotherapy alongside functional and role scales. A new approach is to measure the autonomic state of regulation with the trait-inventory of autonomic regulation (Trait-aR). Loss of Trait-aR has been shown in different medical conditions such as breast cancer (BC) but not in colorectal cancer patients (CRC). In this paper we report the validation of a new state autonomic regulation scale (State-aR) of the last week.</p> <p>Methods</p> <p>Study 1 included 114 participants: (41 women/16 men with cancer and 57 age- and gender-matched healthy people) to conduct a reliability-, factor- and validity-analysis. Concurrent and convergent validity was evaluated with Trait-aR, Fatigue-Numeri-cal-Scale, Hospital Anxiety and Depression Scale (HADS-D) and the self-regulation scale, 65 participants were retested. Study 2 completed 42 participants: 17 with BC and 25 with CRC receiving chemotherapy. The State-aR was administered prior, during and after chemotherapy for measuring responsiveness.</p> <p>Results</p> <p>The factor analysis loaded to four subscales of State-aR (rest-activity, orthostatic-circulatory, thermosweating and digestive regulation) with a: Cronbach-α r<sub>α </sub>= 0.77-0.83 and a test-retest-reliability r<sub>rt </sub>= 0.60-0.80. The sum- and sub scales correlated with their concurrent subscales in the Trait-aR (0.48-0.74) and with the sum-scale moderately with all convergent criteria (r = 0.41 --0.44; p < 0.001). During chemotherapy the State-aR-sum and rest-activity-scale decreased significantly compared to the change in the Trait-aR (p < 0.05).</p> <p>Conclusions</p> <p>These findings support that the state autonomic regulation scale has satisfactory to good reliability, good validity and acceptable responsiveness in the context of chemotherapy treatment.</p>http://www.eurjmedres.com/content/16/10/457CancerCancer-related-fatigue(Trait and State) autonomic regulation (aR)health related quality of lifevalidation study |
| spellingShingle | Kröz M Schad F Reif M von Laue HB Feder G Zerm R Willich SN Girke M Brinkhaus B Validation of the state version questionnaire on autonomic regulation (state-aR) for cancer patients European Journal of Medical Research Cancer Cancer-related-fatigue (Trait and State) autonomic regulation (aR) health related quality of life validation study |
| title | Validation of the state version questionnaire on autonomic regulation (state-aR) for cancer patients |
| title_full | Validation of the state version questionnaire on autonomic regulation (state-aR) for cancer patients |
| title_fullStr | Validation of the state version questionnaire on autonomic regulation (state-aR) for cancer patients |
| title_full_unstemmed | Validation of the state version questionnaire on autonomic regulation (state-aR) for cancer patients |
| title_short | Validation of the state version questionnaire on autonomic regulation (state-aR) for cancer patients |
| title_sort | validation of the state version questionnaire on autonomic regulation state ar for cancer patients |
| topic | Cancer Cancer-related-fatigue (Trait and State) autonomic regulation (aR) health related quality of life validation study |
| url | http://www.eurjmedres.com/content/16/10/457 |
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