Three-in-one procedure for failed spinal surgery improved pain, disability scores and serum inflammatory milieu: Three-years follow-up
ABSTRACTBackground None of the various treatment modalities for failed back surgery syndrome (FBSS) is satisfactory.Aim of the study Comparison of subjective and laboratory outcomes of the 3-in-1 procedure to percutaneous screw and rod spinal fixation (PSRF) for FBSS patients determined at the end o...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-01-01
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| Series: | Egyptian Journal of Anaesthesia |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/11101849.2021.1972259 |
| _version_ | 1797683828799569920 |
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| author | Ossama Hamdy Ahmed E. Salem |
| author_facet | Ossama Hamdy Ahmed E. Salem |
| author_sort | Ossama Hamdy |
| collection | DOAJ |
| description | ABSTRACTBackground None of the various treatment modalities for failed back surgery syndrome (FBSS) is satisfactory.Aim of the study Comparison of subjective and laboratory outcomes of the 3-in-1 procedure to percutaneous screw and rod spinal fixation (PSRF) for FBSS patients determined at the end of Phase II of the study (3-year follow-up after surgery).Patients & Methods This is phase II (follow-up at 3 years) of patients undergoing 3-in-1 procedure (Group B) or PSRF (Group A) as regard pain and disability scores and cytokines levels.Results At phase of the study, pain and disability scores were still significantly lower in all patients with significantly lower scores in group B than in group A. In comparison to the results obtained at the end of Phase I, the 3-in-1 procedure provided better outcome than PSRF only and number of patients graded the outcome as excellent-to-good was significantly higher than in patients of group B than group A. At the end of both phases, serum inflammatory cytokines’ levels were significantly decreased and anti-inflammatory cytokines’ levels were significantly increased in all patients compared to preoperative levels with significant difference in favor of patients of group B. the percentages of change in pain and disability scores at end of Phase II were significantly correlated with the percentage of change of serum anti-inflammatory cytokines’ levels in both groups.Conclusion After 36 m after the 3-in-1 procedure pain scores were significantly decreased with improved disability scores and inflammatory milieu than in patients having FBSS only. |
| first_indexed | 2024-03-12T00:20:30Z |
| format | Article |
| id | doaj.art-b92ddae810cb45d3b201a2033ac22bd2 |
| institution | Directory Open Access Journal |
| issn | 1110-1849 |
| language | English |
| last_indexed | 2024-03-12T00:20:30Z |
| publishDate | 2021-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Egyptian Journal of Anaesthesia |
| spelling | doaj.art-b92ddae810cb45d3b201a2033ac22bd22023-09-15T13:38:33ZengTaylor & Francis GroupEgyptian Journal of Anaesthesia1110-18492021-01-0137144545310.1080/11101849.2021.1972259Three-in-one procedure for failed spinal surgery improved pain, disability scores and serum inflammatory milieu: Three-years follow-upOssama Hamdy0Ahmed E. Salem1Department of Anesthesia, Icu and Pain Management, School of Medicine, South Valley University, Qena, EgyptDepartment of Anesthesiology & Icu, Faculty of Medicine, Tanta University, Tanta, EgyptABSTRACTBackground None of the various treatment modalities for failed back surgery syndrome (FBSS) is satisfactory.Aim of the study Comparison of subjective and laboratory outcomes of the 3-in-1 procedure to percutaneous screw and rod spinal fixation (PSRF) for FBSS patients determined at the end of Phase II of the study (3-year follow-up after surgery).Patients & Methods This is phase II (follow-up at 3 years) of patients undergoing 3-in-1 procedure (Group B) or PSRF (Group A) as regard pain and disability scores and cytokines levels.Results At phase of the study, pain and disability scores were still significantly lower in all patients with significantly lower scores in group B than in group A. In comparison to the results obtained at the end of Phase I, the 3-in-1 procedure provided better outcome than PSRF only and number of patients graded the outcome as excellent-to-good was significantly higher than in patients of group B than group A. At the end of both phases, serum inflammatory cytokines’ levels were significantly decreased and anti-inflammatory cytokines’ levels were significantly increased in all patients compared to preoperative levels with significant difference in favor of patients of group B. the percentages of change in pain and disability scores at end of Phase II were significantly correlated with the percentage of change of serum anti-inflammatory cytokines’ levels in both groups.Conclusion After 36 m after the 3-in-1 procedure pain scores were significantly decreased with improved disability scores and inflammatory milieu than in patients having FBSS only.https://www.tandfonline.com/doi/10.1080/11101849.2021.1972259Failed back surgery syndromecytokinespain scoresdisability scorespercutaneous screw and rod spinal fixationthermal radiofrequency |
| spellingShingle | Ossama Hamdy Ahmed E. Salem Three-in-one procedure for failed spinal surgery improved pain, disability scores and serum inflammatory milieu: Three-years follow-up Egyptian Journal of Anaesthesia Failed back surgery syndrome cytokines pain scores disability scores percutaneous screw and rod spinal fixation thermal radiofrequency |
| title | Three-in-one procedure for failed spinal surgery improved pain, disability scores and serum inflammatory milieu: Three-years follow-up |
| title_full | Three-in-one procedure for failed spinal surgery improved pain, disability scores and serum inflammatory milieu: Three-years follow-up |
| title_fullStr | Three-in-one procedure for failed spinal surgery improved pain, disability scores and serum inflammatory milieu: Three-years follow-up |
| title_full_unstemmed | Three-in-one procedure for failed spinal surgery improved pain, disability scores and serum inflammatory milieu: Three-years follow-up |
| title_short | Three-in-one procedure for failed spinal surgery improved pain, disability scores and serum inflammatory milieu: Three-years follow-up |
| title_sort | three in one procedure for failed spinal surgery improved pain disability scores and serum inflammatory milieu three years follow up |
| topic | Failed back surgery syndrome cytokines pain scores disability scores percutaneous screw and rod spinal fixation thermal radiofrequency |
| url | https://www.tandfonline.com/doi/10.1080/11101849.2021.1972259 |
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