PARKINSON’S DISEASE: ANIMAL MODELS AND DOPAMINERGIC CELL VULNERABILITY
Parkinson's disease (PD) is a neurodegenerative disorder that affects about 1.5% of the global population over 65 years of age. A hallmark feature of PD is the degeneration of the dopamine (DA) neurons in the substantia nigra pars compacta (SNc) and the consequent striatal DA deficiency. Yet, t...
Main Authors: | Javier eBlesa, Serge ePrzedborski |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-12-01
|
Series: | Frontiers in Neuroanatomy |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnana.2014.00155/full |
Similar Items
-
TRH Analog, Taltirelin Protects Dopaminergic Neurons From Neurotoxicity of MPTP and Rotenone
by: Cong Zheng, et al.
Published: (2018-12-01) -
Corynoxine Protects Dopaminergic Neurons Through Inducing Autophagy and Diminishing Neuroinflammation in Rotenone-Induced Animal Models of Parkinson’s Disease
by: Leilei Chen, et al.
Published: (2021-04-01) -
Parkinson's disease: Cell Vulnerability and Disease Progression
by: Javier eBlesa, et al.
Published: (2015-09-01) -
Application of neurotoxin- and pesticide-induced animal models of Parkinson’s disease in the evaluation of new drug delivery systems
by: Casanova Yaquelyn, et al.
Published: (2022-03-01) -
Neuron-selective changes in RNA transcripts related to energy metabolism in toxic models of parkinsonism in rodents
by: James G. Greene, et al.
Published: (2010-06-01)