Structural basis for effector transmembrane domain recognition by type VI secretion system chaperones

Structural basis for effector transmembrane domain recognition by type VI secretion system chaperones

Type VI secretion systems (T6SSs) deliver antibacterial effector proteins between neighboring bacteria. Many effectors harbor N-terminal transmembrane domains (TMDs) implicated in effector translocation across target cell membranes. However, the distribution of these TMD-containing effectors remains...

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Bibliographic Details
Main Authors: Shehryar Ahmad, Kara K Tsang, Kartik Sachar, Dennis Quentin, Tahmid M Tashin, Nathan P Bullen, Stefan Raunser, Andrew G McArthur, Gerd Prehna, John C Whitney
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-12-01
Series:eLife
Subjects:
molecular chaperones
type VI secretion system
x-ray crystallography
protein transport
Gram-negative bacteria
interbacterial competition
Online Access:https://elifesciences.org/articles/62816

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