Prospects for the use of disintegrated membranes of Yersinia pseudotuberculosis, Yersinia enterocolitica and specific antibodies derived from them

It has been established that disintegrated membranes (DM) of pseudotuberculosis and intestinal Yersiniosis microbes can be used to produce highly active hyperimmune sera. Hyperimmune serum obtained as a result of immunization of rabbits with pseudotuberculosis DM showed specificity for Yersinia pseu...

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Main Authors: Kuznetsova Vera, Ivaschenko Sergey
Format: Article
Language:English
Published: EDP Sciences 2020-01-01
Series:E3S Web of Conferences
Online Access:https://www.e3s-conferences.org/articles/e3sconf/pdf/2020/35/e3sconf_interagromash2020_03010.pdf
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author Kuznetsova Vera
Ivaschenko Sergey
author_facet Kuznetsova Vera
Ivaschenko Sergey
author_sort Kuznetsova Vera
collection DOAJ
description It has been established that disintegrated membranes (DM) of pseudotuberculosis and intestinal Yersiniosis microbes can be used to produce highly active hyperimmune sera. Hyperimmune serum obtained as a result of immunization of rabbits with pseudotuberculosis DM showed specificity for Yersinia pseudotuberculosis cells, and serum obtained by immunization with intestinal Yersinia DM interacted in ELISA with Yersinia enterocolitica and Yersinia pseudotuberculosis cells. Antibody titers with bacterial cells of other genus of intestinal microflora were low, which allows the use of the obtained hyperimmune sera to create diagnostic yersiniosis test systems with specific and generic specificity.
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spelling doaj.art-b93de5d106854b488c48efd3efc9edc22022-12-22T03:14:53ZengEDP SciencesE3S Web of Conferences2267-12422020-01-011750301010.1051/e3sconf/202017503010e3sconf_interagromash2020_03010Prospects for the use of disintegrated membranes of Yersinia pseudotuberculosis, Yersinia enterocolitica and specific antibodies derived from themKuznetsova Vera0Ivaschenko Sergey1Saratov State Agrarian University named after N.I. VavilovaSaratov State Agrarian University named after N.I. VavilovaIt has been established that disintegrated membranes (DM) of pseudotuberculosis and intestinal Yersiniosis microbes can be used to produce highly active hyperimmune sera. Hyperimmune serum obtained as a result of immunization of rabbits with pseudotuberculosis DM showed specificity for Yersinia pseudotuberculosis cells, and serum obtained by immunization with intestinal Yersinia DM interacted in ELISA with Yersinia enterocolitica and Yersinia pseudotuberculosis cells. Antibody titers with bacterial cells of other genus of intestinal microflora were low, which allows the use of the obtained hyperimmune sera to create diagnostic yersiniosis test systems with specific and generic specificity.https://www.e3s-conferences.org/articles/e3sconf/pdf/2020/35/e3sconf_interagromash2020_03010.pdf
spellingShingle Kuznetsova Vera
Ivaschenko Sergey
Prospects for the use of disintegrated membranes of Yersinia pseudotuberculosis, Yersinia enterocolitica and specific antibodies derived from them
E3S Web of Conferences
title Prospects for the use of disintegrated membranes of Yersinia pseudotuberculosis, Yersinia enterocolitica and specific antibodies derived from them
title_full Prospects for the use of disintegrated membranes of Yersinia pseudotuberculosis, Yersinia enterocolitica and specific antibodies derived from them
title_fullStr Prospects for the use of disintegrated membranes of Yersinia pseudotuberculosis, Yersinia enterocolitica and specific antibodies derived from them
title_full_unstemmed Prospects for the use of disintegrated membranes of Yersinia pseudotuberculosis, Yersinia enterocolitica and specific antibodies derived from them
title_short Prospects for the use of disintegrated membranes of Yersinia pseudotuberculosis, Yersinia enterocolitica and specific antibodies derived from them
title_sort prospects for the use of disintegrated membranes of yersinia pseudotuberculosis yersinia enterocolitica and specific antibodies derived from them
url https://www.e3s-conferences.org/articles/e3sconf/pdf/2020/35/e3sconf_interagromash2020_03010.pdf
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