The regulation of a pigmentation gene in the formation of complex color patterns in Drosophila abdomens
Changes in the control of developmental gene expression patterns have been implicated in the evolution of animal morphology. However, the genetic mechanisms underlying complex morphological traits remain largely unknown. Here we investigated the molecular mechanisms that induce the pigmentation gene...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2022-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762589/?tool=EBI |
| _version_ | 1797978104561401856 |
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| author | Komal K. B. Raja Mujeeb O. Shittu Peter M. E. Nouhan Tessa E. Steenwinkel Evan A. Bachman Prajakta P. Kokate Alexander McQueeney Elizabeth A. Mundell Alexandri A. Armentrout Amber Nugent Thomas Werner |
| author_facet | Komal K. B. Raja Mujeeb O. Shittu Peter M. E. Nouhan Tessa E. Steenwinkel Evan A. Bachman Prajakta P. Kokate Alexander McQueeney Elizabeth A. Mundell Alexandri A. Armentrout Amber Nugent Thomas Werner |
| author_sort | Komal K. B. Raja |
| collection | DOAJ |
| description | Changes in the control of developmental gene expression patterns have been implicated in the evolution of animal morphology. However, the genetic mechanisms underlying complex morphological traits remain largely unknown. Here we investigated the molecular mechanisms that induce the pigmentation gene yellow in a complex color pattern on the abdomen of Drosophila guttifera. We show that at least five developmental genes may collectively activate one cis-regulatory module of yellow in distinct spot rows and a dark shade to assemble the complete abdominal pigment pattern of Drosophila guttifera. One of these genes, wingless, may play a conserved role in the early phase of spot pattern development in several species of the quinaria group. Our findings shed light on the evolution of complex animal color patterns through modular changes of gene expression patterns. |
| first_indexed | 2024-04-11T05:17:41Z |
| format | Article |
| id | doaj.art-b93e66903e784d4382b7a93eadcef2aa |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-11T05:17:41Z |
| publishDate | 2022-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-b93e66903e784d4382b7a93eadcef2aa2022-12-24T05:33:26ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-011712The regulation of a pigmentation gene in the formation of complex color patterns in Drosophila abdomensKomal K. B. RajaMujeeb O. ShittuPeter M. E. NouhanTessa E. SteenwinkelEvan A. BachmanPrajakta P. KokateAlexander McQueeneyElizabeth A. MundellAlexandri A. ArmentroutAmber NugentThomas WernerChanges in the control of developmental gene expression patterns have been implicated in the evolution of animal morphology. However, the genetic mechanisms underlying complex morphological traits remain largely unknown. Here we investigated the molecular mechanisms that induce the pigmentation gene yellow in a complex color pattern on the abdomen of Drosophila guttifera. We show that at least five developmental genes may collectively activate one cis-regulatory module of yellow in distinct spot rows and a dark shade to assemble the complete abdominal pigment pattern of Drosophila guttifera. One of these genes, wingless, may play a conserved role in the early phase of spot pattern development in several species of the quinaria group. Our findings shed light on the evolution of complex animal color patterns through modular changes of gene expression patterns.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762589/?tool=EBI |
| spellingShingle | Komal K. B. Raja Mujeeb O. Shittu Peter M. E. Nouhan Tessa E. Steenwinkel Evan A. Bachman Prajakta P. Kokate Alexander McQueeney Elizabeth A. Mundell Alexandri A. Armentrout Amber Nugent Thomas Werner The regulation of a pigmentation gene in the formation of complex color patterns in Drosophila abdomens PLoS ONE |
| title | The regulation of a pigmentation gene in the formation of complex color patterns in Drosophila abdomens |
| title_full | The regulation of a pigmentation gene in the formation of complex color patterns in Drosophila abdomens |
| title_fullStr | The regulation of a pigmentation gene in the formation of complex color patterns in Drosophila abdomens |
| title_full_unstemmed | The regulation of a pigmentation gene in the formation of complex color patterns in Drosophila abdomens |
| title_short | The regulation of a pigmentation gene in the formation of complex color patterns in Drosophila abdomens |
| title_sort | regulation of a pigmentation gene in the formation of complex color patterns in drosophila abdomens |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762589/?tool=EBI |
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